Tan DS - Search Results

1

Cheminformatic analysis of natural product-based drugs and chemical probes.

Stone S, Newman DJ, Colletti SL, Tan DS. Stone S, et al. Among authors: tan ds. Nat Prod Rep. 2022 Jan 26;39(1):20-32. doi: 10.1039/d1np00039j. Nat Prod Rep. 2022. PMID: 34342327 Free PMC article. Review.

2

Current progress in natural product-like libraries for discovery screening.

Tan DS. Tan DS. Comb Chem High Throughput Screen. 2004 Nov;7(7):631-43. doi: 10.2174/1386207043328418. Comb Chem High Throughput Screen. 2004. PMID: 15578925 Review.

3

Expanding the range of 'druggable' targets with natural product-based libraries: an academic perspective.

Bauer RA, Wurst JM, Tan DS. Bauer RA, et al. Among authors: tan ds. Curr Opin Chem Biol. 2010 Jun;14(3):308-14. doi: 10.1016/j.cbpa.2010.02.001. Epub 2010 Mar 2. Curr Opin Chem Biol. 2010. PMID: 20202892 Free PMC article. Review.

4

Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion.

Bauer RA, Wenderski TA, Tan DS. Bauer RA, et al. Among authors: tan ds. Nat Chem Biol. 2013 Jan;9(1):21-9. doi: 10.1038/nchembio.1130. Epub 2012 Nov 18. Nat Chem Biol. 2013. PMID: 23160003 Free PMC article.

5

Principal component analysis as a tool for library design: a case study investigating natural products, brand-name drugs, natural product-like libraries, and drug-like libraries.

Wenderski TA, Stratton CF, Bauer RA, Kopp F, Tan DS. Wenderski TA, et al. Among authors: tan ds. Methods Mol Biol. 2015;1263:225-42. doi: 10.1007/978-1-4939-2269-7_18. Methods Mol Biol. 2015. PMID: 25618349 Free PMC article.

6

Cheminformatic comparison of approved drugs from natural product versus synthetic origins.

Stratton CF, Newman DJ, Tan DS. Stratton CF, et al. Among authors: tan ds. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4802-4807. doi: 10.1016/j.bmcl.2015.07.014. Epub 2015 Jul 14. Bioorg Med Chem Lett. 2015. PMID: 26254944 Free PMC article.

7

Defining new chemical space for drug penetration into Gram-negative bacteria.

Zhao S, Adamiak JW, Bonifay V, Mehla J, Zgurskaya HI, Tan DS. Zhao S, et al. Among authors: tan ds. Nat Chem Biol. 2020 Dec;16(12):1293-1302. doi: 10.1038/s41589-020-00674-6. Epub 2020 Nov 16. Nat Chem Biol. 2020. PMID: 33199906 Free PMC article. Review.

8

Design and synthesis of a library of C2-substituted sulfamidoadenosines to probe bacterial permeability.

Zhao S, Maceren J, Chung M, Stone S, Geißen R, Boby ML, Sherborne BS, Tan DS. Zhao S, et al. Among authors: tan ds. Bioorg Med Chem Lett. 2024 Jan 1;97:129486. doi: 10.1016/j.bmcl.2023.129486. Epub 2023 Sep 20. Bioorg Med Chem Lett. 2024. PMID: 37734424

9

Design and synthesis of a library of C8-substituted sulfamidoadenosines to probe bacterial permeability.

Yildirim O, Barman D, Chung M, Stone S, Geißen R, Boby ML, Sherborne BS, Tan DS. Yildirim O, et al. Among authors: tan ds. Bioorg Med Chem Lett. 2024 Sep 15;110:129844. doi: 10.1016/j.bmcl.2024.129844. Epub 2024 Jun 6. Bioorg Med Chem Lett. 2024. PMID: 38851357

10

Small molecule inhibition of microbial natural product biosynthesis-an emerging antibiotic strategy.

Cisar JS, Tan DS. Cisar JS, et al. Among authors: tan ds. Chem Soc Rev. 2008 Jul;37(7):1320-9. doi: 10.1039/b702780j. Epub 2008 May 21. Chem Soc Rev. 2008. PMID: 18568158 Free PMC article. Review.

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