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Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.
Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, Condliffe D, Harries LW, Katsel P, Haroutunian V, Kaminsky Z, Joachim C, Powell J, Lovestone S, Bennett DA, Schalkwyk LC, Mill J. Lunnon K, et al. Among authors: smith r. Nat Neurosci. 2014 Sep;17(9):1164-70. doi: 10.1038/nn.3782. Epub 2014 Aug 17. Nat Neurosci. 2014. PMID: 25129077 Free PMC article.
Tissue-specific patterns of allelically-skewed DNA methylation.
Marzi SJ, Meaburn EL, Dempster EL, Lunnon K, Paya-Cano JL, Smith RG, Volta M, Troakes C, Schalkwyk LC, Mill J. Marzi SJ, et al. Epigenetics. 2016;11(1):24-35. doi: 10.1080/15592294.2015.1127479. Epub 2016 Jan 19. Epigenetics. 2016. PMID: 26786711 Free PMC article.
DNA Modifications and Alzheimer's Disease.
Smith RG, Lunnon K. Smith RG, et al. Adv Exp Med Biol. 2017;978:303-319. doi: 10.1007/978-3-319-53889-1_16. Adv Exp Med Biol. 2017. PMID: 28523553 Review.
Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.
Smith RG, Hannon E, De Jager PL, Chibnik L, Lott SJ, Condliffe D, Smith AR, Haroutunian V, Troakes C, Al-Sarraj S, Bennett DA, Powell J, Lovestone S, Schalkwyk L, Mill J, Lunnon K. Smith RG, et al. Among authors: smith ar. Alzheimers Dement. 2018 Dec;14(12):1580-1588. doi: 10.1016/j.jalz.2018.01.017. Epub 2018 Mar 15. Alzheimers Dement. 2018. PMID: 29550519 Free PMC article.
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