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Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure.
Zhang IW, Curto A, López-Vicario C, Casulleras M, Duran-Güell M, Flores-Costa R, Colsch B, Aguilar F, Aransay AM, Lozano JJ, Hernández-Tejero M, Toapanta D, Fernández J, Arroyo V, Clària J. Zhang IW, et al. Among authors: flores costa r. J Hepatol. 2022 Jan;76(1):93-106. doi: 10.1016/j.jhep.2021.08.009. Epub 2021 Aug 25. J Hepatol. 2022. PMID: 34450236 Free article.
Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease.
López-Vicario C, Sebastián D, Casulleras M, Duran-Güell M, Flores-Costa R, Aguilar F, Lozano JJ, Zhang IW, Titos E, Kang JX, Zorzano A, Arita M, Clària J. López-Vicario C, et al. Among authors: flores costa r. Hepatology. 2023 Apr 1;77(4):1303-1318. doi: 10.1002/hep.32647. Epub 2022 Jul 15. Hepatology. 2023. PMID: 35788956 Free article.
The soluble guanylate cyclase stimulator IW-1973 prevents inflammation and fibrosis in experimental non-alcoholic steatohepatitis.
Flores-Costa R, Alcaraz-Quiles J, Titos E, López-Vicario C, Casulleras M, Duran-Güell M, Rius B, Diaz A, Hall K, Shea C, Sarno R, Currie M, Masferrer JL, Clària J. Flores-Costa R, et al. Br J Pharmacol. 2018 Mar;175(6):953-967. doi: 10.1111/bph.14137. Epub 2018 Jan 31. Br J Pharmacol. 2018. PMID: 29281143 Free PMC article.
Leukocytes from obese individuals exhibit an impaired SPM signature.
López-Vicario C, Titos E, Walker ME, Alcaraz-Quiles J, Casulleras M, Durán-Güell M, Flores-Costa R, Pérez-Romero N, Forné M, Dalli J, Clària J. López-Vicario C, et al. FASEB J. 2019 Jun;33(6):7072-7083. doi: 10.1096/fj.201802587R. Epub 2019 Mar 6. FASEB J. 2019. PMID: 30840838 Free article.
Albumin protects the liver from tumor necrosis factor α-induced immunopathology.
Duran-Güell M, Flores-Costa R, Casulleras M, López-Vicario C, Titos E, Díaz A, Alcaraz-Quiles J, Horrillo R, Costa M, Fernández J, Arroyo V, Clària J. Duran-Güell M, et al. Among authors: flores costa r. FASEB J. 2021 Feb;35(2):e21365. doi: 10.1096/fj.202001615RRR. FASEB J. 2021. PMID: 33496031
Proresolving lipid mediators and liver disease.
Clària J, Flores-Costa R, Duran-Güell M, López-Vicario C. Clària J, et al. Among authors: flores costa r. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Nov;1866(11):159023. doi: 10.1016/j.bbalip.2021.159023. Epub 2021 Aug 2. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 34352389 Free article. Review.
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