El-Morsy AM - Search Results

1

Pharmacophore-linked pyrazolo[3,4-d]pyrimidines as EGFR-TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies.

Gaber AA, El-Morsy AM, Sherbiny FF, Bayoumi AH, El-Gamal KM, El-Adl K, Al-Karmalawy AA, Ezz Eldin RR, Saleh MA, Abulkhair HS. Gaber AA, et al. Among authors: el morsy am. Arch Pharm (Weinheim). 2021 Aug 31:e2100258. doi: 10.1002/ardp.202100258. Online ahead of print. Arch Pharm (Weinheim). 2021. PMID: 34467546

2

Synthesis and Biological Evaluation of Some [1,2,4]Triazolo[4,3-a]quinoxaline Derivatives as Novel Anticonvulsant Agents.

Alswah M, Ghiaty A, El-Morsy A, El-Gamal K. Alswah M, et al. ISRN Org Chem. 2013 Sep 12;2013:587054. doi: 10.1155/2013/587054. eCollection 2013. ISRN Org Chem. 2013. PMID: 24198971 Free PMC article.

3

Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.

Alswah M, Bayoumi AH, Elgamal K, Elmorsy A, Ihmaid S, Ahmed HEA. Alswah M, et al. Molecules. 2017 Dec 27;23(1):48. doi: 10.3390/molecules23010048. Molecules. 2017. PMID: 29280968 Free PMC article.

4

Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFR^WT and EGFR^T790M inhibitors and apoptosis inducers.

Gaber AA, Bayoumi AH, El-Morsy AM, Sherbiny FF, Mehany ABM, Eissa IH. Gaber AA, et al. Among authors: el morsy am. Bioorg Chem. 2018 Oct;80:375-395. doi: 10.1016/j.bioorg.2018.06.017. Epub 2018 Jun 12. Bioorg Chem. 2018. PMID: 29986185

5

Antimicrobial screening and pharmacokinetic profiling of novel phenyl-[1,2,4]triazolo[4,3-a]quinoxaline analogues targeting DHFR and E. coli DNA gyrase B.

Omar AM, Alswah M, Ahmed HEA, Bayoumi AH, El-Gamal KM, El-Morsy A, Ghiaty A, Afifi TH, Sherbiny FF, Mohammed AS, Mansour BA. Omar AM, et al. Bioorg Chem. 2020 Mar;96:103656. doi: 10.1016/j.bioorg.2020.103656. Epub 2020 Feb 10. Bioorg Chem. 2020. PMID: 32062449

6

Design, synthesis, and molecular docking studies of new [1,2,4]triazolo[4,3-a]quinoxaline derivatives as potential A2B receptor antagonists.

Ezzat HG, Bayoumi AH, Sherbiny FF, El-Morsy AM, Ghiaty A, Alswah M, Abulkhair HS. Ezzat HG, et al. Among authors: el morsy am. Mol Divers. 2021 Feb;25(1):291-306. doi: 10.1007/s11030-020-10070-w. Epub 2020 Mar 12. Mol Divers. 2021. PMID: 32166485

7

In vivo- and in silico-driven identification of novel synthetic quinoxalines as anticonvulsants and AMPA inhibitors.

Abulkhair HS, Elmeligie S, Ghiaty A, El-Morsy A, Bayoumi AH, Ahmed HEA, El-Adl K, Zayed MF, Hassan MH, Akl EN, El-Zoghbi MS. Abulkhair HS, et al. Arch Pharm (Weinheim). 2021 May;354(5):e2000449. doi: 10.1002/ardp.202000449. Epub 2021 Feb 9. Arch Pharm (Weinheim). 2021. PMID: 33559320

8

Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers.

Sherbiny FF, Bayoumi AH, El-Morsy AM, Sobhy M, Hagras M. Sherbiny FF, et al. Among authors: el morsy am. Bioorg Chem. 2021 Nov;116:105325. doi: 10.1016/j.bioorg.2021.105325. Epub 2021 Sep 4. Bioorg Chem. 2021. PMID: 34507234

9

Triazoloquinoxalines-based DNA intercalators-Topo II inhibitors: design, synthesis, docking, ADMET and anti-proliferative evaluations.

Elwan A, Sakr H, El-Helby AA, El-Morsy A, Abdelgawad MA, Ghoneim MM, El-Sherbiny M, El-Adl K. Elwan A, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1556-1567. doi: 10.1080/14756366.2022.2080205. J Enzyme Inhib Med Chem. 2022. PMID: 35635148 Free PMC article.

10

Development of Novel Class of Phenylpyrazolo[3,4-d]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by Docking Studies.

Aljohani AKB, El Zaloa WAZ, Alswah M, Seleem MA, Elsebaei MM, Bayoumi AH, El-Morsy AM, Almaghrabi M, Awaji AA, Hammad A, Alsulaimany M, Ahmed HEA. Aljohani AKB, et al. Among authors: el morsy am. Int J Mol Sci. 2023 Oct 9;24(19):15026. doi: 10.3390/ijms241915026. Int J Mol Sci. 2023. PMID: 37834474 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

23 results

Search Page

Filters