Horton JR - Search Results

1

Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA.

Zhou J, Horton JR, Yu D, Ren R, Blumenthal RM, Zhang X, Cheng X. Zhou J, et al. Among authors: horton jr. Epigenetics. 2022 Sep;17(9):970-981. doi: 10.1080/15592294.2021.1976910. Epub 2021 Sep 15. Epigenetics. 2022. PMID: 34523387 Free PMC article.

2

PvuII endonuclease contains two calcium ions in active sites.

Horton JR, Cheng X. Horton JR, et al. J Mol Biol. 2000 Jul 28;300(5):1049-56. doi: 10.1006/jmbi.2000.3938. J Mol Biol. 2000. PMID: 10903853

3

Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.

Horton JR, Sawada K, Nishibori M, Zhang X, Cheng X. Horton JR, et al. Structure. 2001 Sep;9(9):837-49. doi: 10.1016/s0969-2126(01)00643-8. Structure. 2001. PMID: 11566133 Free PMC article.

4

Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase.

Zhang X, Tamaru H, Khan SI, Horton JR, Keefe LJ, Selker EU, Cheng X. Zhang X, et al. Among authors: horton jr. Cell. 2002 Oct 4;111(1):117-27. doi: 10.1016/s0092-8674(02)00999-6. Cell. 2002. PMID: 12372305 Free PMC article.

5

Structural basis for the product specificity of histone lysine methyltransferases.

Zhang X, Yang Z, Khan SI, Horton JR, Tamaru H, Selker EU, Cheng X. Zhang X, et al. Among authors: horton jr. Mol Cell. 2003 Jul;12(1):177-85. doi: 10.1016/s1097-2765(03)00224-7. Mol Cell. 2003. PMID: 12887903 Free PMC article.

6

Structure of the bacteriophage T4 DNA adenine methyltransferase.

Yang Z, Horton JR, Zhou L, Zhang XJ, Dong A, Zhang X, Schlagman SL, Kossykh V, Hattman S, Cheng X. Yang Z, et al. Among authors: horton jr. Nat Struct Biol. 2003 Oct;10(10):849-55. doi: 10.1038/nsb973. Epub 2003 Aug 24. Nat Struct Biol. 2003. PMID: 12937411 Free PMC article.

7

Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase.

Sawada K, Yang Z, Horton JR, Collins RE, Zhang X, Cheng X. Sawada K, et al. Among authors: horton jr. J Biol Chem. 2004 Oct 8;279(41):43296-306. doi: 10.1074/jbc.M405902200. Epub 2004 Jul 29. J Biol Chem. 2004. PMID: 15292170 Free PMC article.

8

Transition from nonspecific to specific DNA interactions along the substrate-recognition pathway of dam methyltransferase.

Horton JR, Liebert K, Hattman S, Jeltsch A, Cheng X. Horton JR, et al. Cell. 2005 May 6;121(3):349-61. doi: 10.1016/j.cell.2005.02.021. Cell. 2005. PMID: 15882618 Free PMC article.

9

Structural basis for inhibition of histamine N-methyltransferase by diverse drugs.

Horton JR, Sawada K, Nishibori M, Cheng X. Horton JR, et al. J Mol Biol. 2005 Oct 21;353(2):334-344. doi: 10.1016/j.jmb.2005.08.040. J Mol Biol. 2005. PMID: 16168438 Free PMC article.

10

Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase.

Horton JR, Liebert K, Bekes M, Jeltsch A, Cheng X. Horton JR, et al. J Mol Biol. 2006 Apr 28;358(2):559-70. doi: 10.1016/j.jmb.2006.02.028. Epub 2006 Feb 28. J Mol Biol. 2006. PMID: 16524590 Free PMC article.

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