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Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis.
Oliveira PH, Ribis JW, Garrett EM, Trzilova D, Kim A, Sekulovic O, Mead EA, Pak T, Zhu S, Deikus G, Touchon M, Lewis-Sandari M, Beckford C, Zeitouni NE, Altman DR, Webster E, Oussenko I, Bunyavanich S, Aggarwal AK, Bashir A, Patel G, Wallach F, Hamula C, Huprikar S, Schadt EE, Sebra R, van Bakel H, Kasarskis A, Tamayo R, Shen A, Fang G. Oliveira PH, et al. Among authors: tamayo r. Nat Microbiol. 2020 Jan;5(1):166-180. doi: 10.1038/s41564-019-0613-4. Epub 2019 Nov 25. Nat Microbiol. 2020. PMID: 31768029 Free PMC article.
c-di-GMP Inhibits Early Sporulation in Clostridioides difficile.
Edwards AN, Willams CL, Pareek N, McBride SM, Tamayo R. Edwards AN, et al. Among authors: tamayo r. mSphere. 2021 Dec 22;6(6):e0091921. doi: 10.1128/msphere.00919-21. Epub 2021 Dec 8. mSphere. 2021. PMID: 34878288 Free PMC article.
Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation.
Furtado KL, Plott L, Markovetz M, Powers D, Wang H, Hill DB, Papin J, Allbritton NL, Tamayo R. Furtado KL, et al. Among authors: tamayo r. bioRxiv [Preprint]. 2024 Feb 3:2024.02.01.578425. doi: 10.1101/2024.02.01.578425. bioRxiv. 2024. Update in: mSphere. 2024 Jun 25;9(6):e0008124. doi: 10.1128/msphere.00081-24. PMID: 38352512 Free PMC article. Updated. Preprint.
138 results