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Page 1
Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization.
Sullivan WJ, Mullen PJ, Schmid EW, Flores A, Momcilovic M, Sharpley MS, Jelinek D, Whiteley AE, Maxwell MB, Wilde BR, Banerjee U, Coller HA, Shackelford DB, Braas D, Ayer DE, de Aguiar Vallim TQ, Lowry WE, Christofk HR. Sullivan WJ, et al. Among authors: christofk hr. Cell. 2018 Sep 20;175(1):117-132.e21. doi: 10.1016/j.cell.2018.08.017. Epub 2018 Sep 6. Cell. 2018. PMID: 30197082 Free PMC article.
O-Mg! Lactate Drives Mg2+ Mobilization.
Wilde BR, Christofk HR. Wilde BR, et al. Among authors: christofk hr. Mol Cell. 2020 Dec 3;80(5):762-763. doi: 10.1016/j.molcel.2020.11.023. Mol Cell. 2020. PMID: 33275887 Free article.
ZFP36-mediated mRNA decay regulates metabolism.
Cicchetto AC, Jacobson EC, Sunshine H, Wilde BR, Krall AS, Jarrett KE, Sedgeman L, Turner M, Plath K, Iruela-Arispe ML, de Aguiar Vallim TQ, Christofk HR. Cicchetto AC, et al. Among authors: christofk hr. Cell Rep. 2023 May 30;42(5):112411. doi: 10.1016/j.celrep.2023.112411. Epub 2023 Apr 21. Cell Rep. 2023. PMID: 37086408 Free PMC article.
MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer.
Crowell PD, Giafaglione JM, Jones AE, Nunley NM, Hashimoto T, Delcourt AML, Petcherski A, Agrawal R, Bernard MJ, Diaz JA, Heering KY, Huang RR, Low JY, Matulionis N, Navone NM, Ye H, Zoubeidi A, Christofk HR, Rettig MB, Reiter RE, Haffner MC, Boutros PC, Shirihai OS, Divakaruni AS, Goldstein AS. Crowell PD, et al. Among authors: christofk hr. Cell Rep. 2023 Oct 31;42(10):113221. doi: 10.1016/j.celrep.2023.113221. Epub 2023 Oct 9. Cell Rep. 2023. PMID: 37815914 Free article.
Targeting Asparagine Metabolism in Well-Differentiated/Dedifferentiated Liposarcoma.
Klingbeil KD, Wilde BR, Graham DS, Lofftus S, McCaw T, Matulionis N, Dry SM, Crompton JG, Eilber FC, Graeber TG, Shackelford DB, Christofk HR, Kadera BE. Klingbeil KD, et al. Among authors: christofk hr. Cancers (Basel). 2024 Aug 30;16(17):3031. doi: 10.3390/cancers16173031. Cancers (Basel). 2024. PMID: 39272889 Free PMC article.
An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity.
Williams KJ, Argus JP, Zhu Y, Wilks MQ, Marbois BN, York AG, Kidani Y, Pourzia AL, Akhavan D, Lisiero DN, Komisopoulou E, Henkin AH, Soto H, Chamberlain BT, Vergnes L, Jung ME, Torres JZ, Liau LM, Christofk HR, Prins RM, Mischel PS, Reue K, Graeber TG, Bensinger SJ. Williams KJ, et al. Among authors: christofk hr. Cancer Res. 2013 May 1;73(9):2850-62. doi: 10.1158/0008-5472.CAN-13-0382-T. Epub 2013 Feb 25. Cancer Res. 2013. PMID: 23440422 Free PMC article.
Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer.
Garon EB, Christofk HR, Hosmer W, Britten CD, Bahng A, Crabtree MJ, Hong CS, Kamranpour N, Pitts S, Kabbinavar F, Patel C, von Euw E, Black A, Michelakis ED, Dubinett SM, Slamon DJ. Garon EB, et al. Among authors: christofk hr. J Cancer Res Clin Oncol. 2014 Mar;140(3):443-52. doi: 10.1007/s00432-014-1583-9. Epub 2014 Jan 18. J Cancer Res Clin Oncol. 2014. PMID: 24442098 Free PMC article. Clinical Trial.
81 results