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Human MAIT cells respond to and suppress HIV-1.
Phetsouphanh C, Phalora P, Hackstein CP, Thornhill J, Munier CML, Meyerowitz J, Murray L, VanVuuren C, Goedhals D, Drexhage L, Moore R, Sattentau QJ, Mak JY, Fairlie DP, Fidler S, Kelleher AD, Frater J, Klenerman P. Phetsouphanh C, et al. Among authors: fairlie dp. Elife. 2021 Dec 24;10:e50324. doi: 10.7554/eLife.50324. Elife. 2021. PMID: 34951583 Free PMC article.
T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
Corbett AJ, Eckle SB, Birkinshaw RW, Liu L, Patel O, Mahony J, Chen Z, Reantragoon R, Meehan B, Cao H, Williamson NA, Strugnell RA, Van Sinderen D, Mak JY, Fairlie DP, Kjer-Nielsen L, Rossjohn J, McCluskey J. Corbett AJ, et al. Among authors: fairlie dp. Nature. 2014 May 15;509(7500):361-5. doi: 10.1038/nature13160. Epub 2014 Apr 2. Nature. 2014. PMID: 24695216
Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation.
Loh L, Wang Z, Sant S, Koutsakos M, Jegaskanda S, Corbett AJ, Liu L, Fairlie DP, Crowe J, Rossjohn J, Xu J, Doherty PC, McCluskey J, Kedzierska K. Loh L, et al. Among authors: fairlie dp. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10133-8. doi: 10.1073/pnas.1610750113. Epub 2016 Aug 19. Proc Natl Acad Sci U S A. 2016. PMID: 27543331 Free PMC article.
PAR2 Modulators Derived from GB88.
Yau MK, Liu L, Suen JY, Lim J, Lohman RJ, Jiang Y, Cotterell AJ, Barry GD, Mak JY, Vesey DA, Reid RC, Fairlie DP. Yau MK, et al. Among authors: fairlie dp. ACS Med Chem Lett. 2016 Oct 10;7(12):1179-1184. doi: 10.1021/acsmedchemlett.6b00306. eCollection 2016 Dec 8. ACS Med Chem Lett. 2016. PMID: 27994760 Free PMC article.
Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Keller AN, Eckle SB, Xu W, Liu L, Hughes VA, Mak JY, Meehan BS, Pediongco T, Birkinshaw RW, Chen Z, Wang H, D'Souza C, Kjer-Nielsen L, Gherardin NA, Godfrey DI, Kostenko L, Corbett AJ, Purcell AW, Fairlie DP, McCluskey J, Rossjohn J. Keller AN, et al. Among authors: fairlie dp. Nat Immunol. 2017 Apr;18(4):402-411. doi: 10.1038/ni.3679. Epub 2017 Feb 6. Nat Immunol. 2017. PMID: 28166217
Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection.
D'Souza C, Pediongco T, Wang H, Scheerlinck JY, Kostenko L, Esterbauer R, Stent AW, Eckle SBG, Meehan BS, Strugnell RA, Cao H, Liu L, Mak JYW, Lovrecz G, Lu L, Fairlie DP, Rossjohn J, McCluskey J, Every AL, Chen Z, Corbett AJ. D'Souza C, et al. Among authors: fairlie dp. J Immunol. 2018 Mar 1;200(5):1901-1916. doi: 10.4049/jimmunol.1701512. Epub 2018 Jan 29. J Immunol. 2018. PMID: 29378910
Human blood MAIT cell subsets defined using MR1 tetramers.
Gherardin NA, Souter MN, Koay HF, Mangas KM, Seemann T, Stinear TP, Eckle SB, Berzins SP, d'Udekem Y, Konstantinov IE, Fairlie DP, Ritchie DS, Neeson PJ, Pellicci DG, Uldrich AP, McCluskey J, Godfrey DI. Gherardin NA, et al. Among authors: fairlie dp. Immunol Cell Biol. 2018 May;96(5):507-525. doi: 10.1111/imcb.12021. Epub 2018 Mar 25. Immunol Cell Biol. 2018. PMID: 29437263 Free PMC article.
Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma.
Gherardin NA, Loh L, Admojo L, Davenport AJ, Richardson K, Rogers A, Darcy PK, Jenkins MR, Prince HM, Harrison SJ, Quach H, Fairlie DP, Kedzierska K, McCluskey J, Uldrich AP, Neeson PJ, Ritchie DS, Godfrey DI. Gherardin NA, et al. Among authors: fairlie dp. Sci Rep. 2018 Mar 7;8(1):4159. doi: 10.1038/s41598-018-22130-1. Sci Rep. 2018. PMID: 29515123 Free PMC article. Clinical Trial.
400 results