Davis AJ - Search Results

1

Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells.

Spahn PN, Zhang X, Hu Q, Lu H, Hamaker NK, Hefzi H, Li S, Kuo CC, Huang Y, Lee JC, Davis AJ, Ly P, Lee KH, Lewis NE. Spahn PN, et al. Among authors: davis aj. Biotechnol Bioeng. 2022 Mar;119(3):963-982. doi: 10.1002/bit.28016. Epub 2022 Jan 5. Biotechnol Bioeng. 2022. PMID: 34953085 Free PMC article.

2

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

Lu H, Shamanna RA, de Freitas JK, Okur M, Khadka P, Kulikowicz T, Holland PP, Tian J, Croteau DL, Davis AJ, Bohr VA. Lu H, et al. Among authors: davis aj. Nat Commun. 2017 Dec 11;8(1):2039. doi: 10.1038/s41467-017-02146-3. Nat Commun. 2017. PMID: 29229926 Free PMC article.

3

DNA-PKcs promotes chromatin decondensation to facilitate initiation of the DNA damage response.

Lu H, Saha J, Beckmann PJ, Hendrickson EA, Davis AJ. Lu H, et al. Among authors: davis aj. Nucleic Acids Res. 2019 Oct 10;47(18):9467-9479. doi: 10.1093/nar/gkz694. Nucleic Acids Res. 2019. PMID: 31396623 Free PMC article.

4

MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway.

Guan J, Lu C, Jin Q, Lu H, Chen X, Tian L, Zhang Y, Ortega J, Zhang J, Siteni S, Chen M, Gu L, Shay JW, Davis AJ, Chen ZJ, Fu YX, Li GM. Guan J, et al. Among authors: davis aj. Cancer Cell. 2021 Jan 11;39(1):109-121.e5. doi: 10.1016/j.ccell.2020.11.004. Epub 2020 Dec 17. Cancer Cell. 2021. PMID: 33338427 Free PMC article.

5

Human RecQ Helicases in DNA Double-Strand Break Repair.

Lu H, Davis AJ. Lu H, et al. Among authors: davis aj. Front Cell Dev Biol. 2021 Feb 25;9:640755. doi: 10.3389/fcell.2021.640755. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33718381 Free PMC article. Review.

6

Ablating putative Ku70 phosphorylation sites results in defective DNA damage repair and spontaneous induction of hepatocellular carcinoma.

Saha J, Bae J, Wang SY, Lu H, Chappell LJ, Gopal P, Davis AJ. Saha J, et al. Among authors: davis aj. Nucleic Acids Res. 2021 Sep 27;49(17):9836-9850. doi: 10.1093/nar/gkab743. Nucleic Acids Res. 2021. PMID: 34428289 Free PMC article.

7

DNA-PKcs-dependent phosphorylation of RECQL4 promotes NHEJ by stabilizing the NHEJ machinery at DNA double-strand breaks.

Lu H, Guan J, Wang SY, Li GM, Bohr VA, Davis AJ. Lu H, et al. Among authors: davis aj. Nucleic Acids Res. 2022 Jun 10;50(10):5635-5651. doi: 10.1093/nar/gkac375. Nucleic Acids Res. 2022. PMID: 35580045 Free PMC article.

8

Non-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errors.

Hu Q, Espejo Valle-Inclán J, Dahiya R, Guyer A, Mazzagatti A, Maurais EG, Engel JL, Lu H, Davis AJ, Cortés-Ciriano I, Ly P. Hu Q, et al. Among authors: davis aj. Nat Commun. 2024 Jul 4;15(1):5611. doi: 10.1038/s41467-024-49985-5. Nat Commun. 2024. PMID: 38965240 Free PMC article.

9

Persistently bound Ku at DNA ends attenuates DNA end resection and homologous recombination.

Shao Z, Davis AJ, Fattah KR, So S, Sun J, Lee KJ, Harrison L, Yang J, Chen DJ. Shao Z, et al. Among authors: davis aj. DNA Repair (Amst). 2012 Mar 1;11(3):310-6. doi: 10.1016/j.dnarep.2011.12.007. Epub 2012 Jan 20. DNA Repair (Amst). 2012. PMID: 22265216 Free PMC article.

10

The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation.

Davis AJ, Lee KJ, Chen DJ. Davis AJ, et al. J Biol Chem. 2013 Mar 8;288(10):7037-46. doi: 10.1074/jbc.M112.434498. Epub 2013 Jan 15. J Biol Chem. 2013. PMID: 23322783 Free PMC article.

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