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Mechanistic origins of diverse genome rearrangements in cancer.
Dahiya R, Hu Q, Ly P. Dahiya R, et al. Among authors: ly p. Semin Cell Dev Biol. 2022 Mar;123:100-109. doi: 10.1016/j.semcdb.2021.03.003. Epub 2021 Apr 3. Semin Cell Dev Biol. 2022. PMID: 33824062 Free PMC article. Review.
Mitotic clustering of pulverized chromosomes from micronuclei.
Lin YF, Hu Q, Mazzagatti A, Valle-Inclán JE, Maurais EG, Dahiya R, Guyer A, Sanders JT, Engel JL, Nguyen G, Bronder D, Bakhoum SF, Cortés-Ciriano I, Ly P. Lin YF, et al. Among authors: ly p. Nature. 2023 Jun;618(7967):1041-1048. doi: 10.1038/s41586-023-05974-0. Epub 2023 May 10. Nature. 2023. PMID: 37165191 Free PMC article.
Non-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errors.
Hu Q, Valle-Inclan JE, Dahiya R, Guyer A, Mazzagatti A, Maurais EG, Engel JL, Cortés-Ciriano I, Ly P. Hu Q, et al. Among authors: ly p. bioRxiv [Preprint]. 2023 Aug 11:2023.08.10.552800. doi: 10.1101/2023.08.10.552800. bioRxiv. 2023. Update in: Nat Commun. 2024 Jul 4;15(1):5611. doi: 10.1038/s41467-024-49985-5. PMID: 37609143 Free PMC article. Updated. Preprint.
Chromosomal instability drives metastasis through a cytosolic DNA response.
Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, Birkbak NJ, McGranahan N, Lundquist M, LaPlant Q, Healey JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe'er D, Cleveland DW, Powell SN, Lammerding J, Swanton C, Cantley LC. Bakhoum SF, et al. Among authors: ly p. Nature. 2018 Jan 25;553(7689):467-472. doi: 10.1038/nature25432. Epub 2018 Jan 17. Nature. 2018. PMID: 29342134 Free PMC article.
210 results