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Mitogen-activated protein kinase-activated protein kinase 2 mediates apoptosis during lung vascular permeability by regulating movement of cleaved caspase 3.
Damarla M, Parniani AR, Johnston L, Maredia H, Serebreni L, Hamdan O, Sidhaye VK, Shimoda LA, Myers AC, Crow MT, Schmidt EP, Machamer CE, Gaestel M, Rane MJ, Kolb TM, Kim BS, Damico RL, Hassoun PM. Damarla M, et al. Am J Respir Cell Mol Biol. 2014 May;50(5):932-41. doi: 10.1165/rcmb.2013-0361OC. Am J Respir Cell Mol Biol. 2014. PMID: 24304496 Free PMC article.
Reactive oxygen species induced Ca2+ influx via TRPV4 and microvascular endothelial dysfunction in the SU5416/hypoxia model of pulmonary arterial hypertension.
Suresh K, Servinsky L, Jiang H, Bigham Z, Yun X, Kliment C, Huetsch J, Damarla M, Shimoda LA. Suresh K, et al. Among authors: damarla m. Am J Physiol Lung Cell Mol Physiol. 2018 May 1;314(5):L893-L907. doi: 10.1152/ajplung.00430.2017. Epub 2018 Feb 1. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29388466 Free PMC article.
A nonapoptotic endothelial barrier-protective role for caspase-3.
Suresh K, Carino K, Johnston L, Servinsky L, Machamer CE, Kolb TM, Lam H, Dudek SM, An SS, Rane MJ, Shimoda LA, Damarla M. Suresh K, et al. Among authors: damarla m. Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1;316(6):L1118-L1126. doi: 10.1152/ajplung.00487.2018. Epub 2019 Mar 25. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30908935 Free PMC article.
Regulation of mitochondrial fragmentation in microvascular endothelial cells isolated from the SU5416/hypoxia model of pulmonary arterial hypertension.
Suresh K, Servinsky L, Jiang H, Bigham Z, Zaldumbide J, Huetsch JC, Kliment C, Acoba MG, Kirsch BJ, Claypool SM, Le A, Damarla M, Shimoda LA. Suresh K, et al. Among authors: damarla m. Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1;317(5):L639-L652. doi: 10.1152/ajplung.00396.2018. Epub 2019 Aug 28. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 31461316 Free PMC article.
Functional Impact of Human Genetic Variants of COL18A1/Endostatin on Pulmonary Endothelium.
Goyanes AM, Moldobaeva A, Marimoutou M, Varela LC, Wang L, Johnston LF, Aladdin MM, Peloquin GL, Kim BS, Damarla M, Suresh K, Sato T, Kolb TM, Hassoun PM, Damico RL. Goyanes AM, et al. Among authors: damarla m. Am J Respir Cell Mol Biol. 2020 Apr;62(4):524-534. doi: 10.1165/rcmb.2019-0056OC. Am J Respir Cell Mol Biol. 2020. PMID: 31922883 Free PMC article.
Tumor MK2 transcript levels are associated with improved response to chemotherapy and patient survival in non-small cell lung cancer.
Suresh K, Del Rosario O, Kallem M, Singh G, Shah A, Zheng L, Yun X, Philip NM, Putcha N, McClure MB, Jiang H, D'Alessio F, Srivastava M, Bera A, Shimoda LA, Merchant M, Rane MJ, Machamer CE, Mock J, Hagan R, Koch AL, Punjabi NM, Kolb TM, Damarla M. Suresh K, et al. Among authors: damarla m. Physiol Genomics. 2023 Apr 1;55(4):168-178. doi: 10.1152/physiolgenomics.00155.2022. Epub 2023 Mar 6. Physiol Genomics. 2023. PMID: 36878491 Free PMC article.
MK2 nonenzymatically promotes nuclear translocation of caspase-3 and resultant apoptosis.
Del Rosario O, Suresh K, Kallem M, Singh G, Shah A, Zheng L, Yun X, Philip NM, Putcha N, McClure MB, Jiang H, D'Alessio F, Srivastava M, Bera A, Shimoda LA, Merchant M, Rane MJ, Machamer CE, Mock J, Hagan R, Koch AL, Punjabi NM, Kolb TM, Damarla M. Del Rosario O, et al. Among authors: damarla m. Am J Physiol Lung Cell Mol Physiol. 2023 May 1;324(5):L700-L711. doi: 10.1152/ajplung.00340.2022. Epub 2023 Mar 28. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 36976920 Free PMC article.
50 results