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Pediatric multicellular tumor spheroid models illustrate a therapeutic potential by combining BH3 mimetics with Natural Killer (NK) cell-based immunotherapy.
Särchen V, Shanmugalingam S, Kehr S, Reindl LM, Greze V, Wiedemann S, Boedicker C, Jacob M, Bankov K, Becker N, Wehner S, Theilen TM, Gretser S, Gradhand E, Kummerow C, Ullrich E, Vogler M. Särchen V, et al. Among authors: kummerow c. Cell Death Discov. 2022 Jan 10;8(1):11. doi: 10.1038/s41420-021-00812-6. Cell Death Discov. 2022. PMID: 35013156 Free PMC article.
A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity.
Zhou X, Friedmann KS, Lyrmann H, Zhou Y, Schoppmeyer R, Knörck A, Mang S, Hoxha C, Angenendt A, Backes CS, Mangerich C, Zhao R, Cappello S, Schwär G, Hässig C, Neef M, Bufe B, Zufall F, Kruse K, Niemeyer BA, Lis A, Qu B, Kummerow C, Schwarz EC, Hoth M. Zhou X, et al. Among authors: kummerow c. J Physiol. 2018 Jul;596(14):2681-2698. doi: 10.1113/JP274964. Epub 2018 Mar 12. J Physiol. 2018. PMID: 29368348 Free PMC article.
Protein Signatures of NK Cell-Mediated Melanoma Killing Predict Response to Immunotherapies.
Cappello S, Sung HM, Ickes C, Gibhardt CS, Vultur A, Bhat H, Hu Z, Brafford P, Denger A, Stejerean-Todoran I, Köhn RM, Lorenz V, Künzel N, Salinas G, Stanisz H, Legler T, Rehling P, Schön MP, Lang KS, Helms V, Herlyn M, Hoth M, Kummerow C, Bogeski I. Cappello S, et al. Among authors: kummerow c. Cancer Res. 2021 Nov 1;81(21):5540-5554. doi: 10.1158/0008-5472.CAN-21-0164. Epub 2021 Sep 13. Cancer Res. 2021. PMID: 34518212 Free PMC article.
The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α.
Tosatto A, Sommaggio R, Kummerow C, Bentham RB, Blacker TS, Berecz T, Duchen MR, Rosato A, Bogeski I, Szabadkai G, Rizzuto R, Mammucari C. Tosatto A, et al. Among authors: kummerow c. EMBO Mol Med. 2016 May 2;8(5):569-85. doi: 10.15252/emmm.201606255. Print 2016 May. EMBO Mol Med. 2016. PMID: 27138568 Free PMC article.
21 results