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Page 1
Therapeutic efficacy of FASN inhibition in preclinical models of HCC.
Wang H, Zhou Y, Xu H, Wang X, Zhang Y, Shang R, O'Farrell M, Roessler S, Sticht C, Stahl A, Evert M, Calvisi DF, Zeng Y, Chen X. Wang H, et al. Among authors: sticht c. Hepatology. 2022 Oct;76(4):951-966. doi: 10.1002/hep.32359. Epub 2022 Feb 16. Hepatology. 2022. PMID: 35076948 Free PMC article.
Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma.
Tschaharganeh DF, Chen X, Latzko P, Malz M, Gaida MM, Felix K, Ladu S, Singer S, Pinna F, Gretz N, Sticht C, Tomasi ML, Delogu S, Evert M, Fan B, Ribback S, Jiang L, Brozzetti S, Bergmann F, Dombrowski F, Schirmacher P, Calvisi DF, Breuhahn K. Tschaharganeh DF, et al. Among authors: sticht c. Gastroenterology. 2013 Jun;144(7):1530-1542.e12. doi: 10.1053/j.gastro.2013.02.009. Epub 2013 Feb 16. Gastroenterology. 2013. PMID: 23419361 Free PMC article.
Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.
Winkler J, Ori A, Holzer K, Sticht C, Dauch D, Eiteneuer EM, Pinna F, Geffers R, Ehemann V, Andres-Pons A, Breuhahn K, Longerich T, Bermejo JL, Gretz N, Zender L, Schirmacher P, Beck M, Singer S. Winkler J, et al. Among authors: sticht c. Hepatology. 2014 Sep;60(3):884-95. doi: 10.1002/hep.27207. Epub 2014 Jul 17. Hepatology. 2014. PMID: 24799195
Overexpression of far upstream element (FUSE) binding protein (FBP)-interacting repressor (FIR) supports growth of hepatocellular carcinoma.
Malz M, Bovet M, Samarin J, Rabenhorst U, Sticht C, Bissinger M, Roessler S, Bermejo JL, Renner M, Calvisi DF, Singer S, Ganzinger M, Weber A, Gretz N, Zörnig M, Schirmacher P, Breuhahn K. Malz M, et al. Among authors: sticht c. Hepatology. 2014 Oct;60(4):1241-50. doi: 10.1002/hep.27218. Epub 2014 Jul 31. Hepatology. 2014. PMID: 24824848
Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC).
Winkler J, Roessler S, Sticht C, DiGuilio AL, Drucker E, Holzer K, Eiteneuer E, Herpel E, Breuhahn K, Gretz N, Schirmacher P, Ori A, Singer S. Winkler J, et al. Among authors: sticht c. Oncotarget. 2016 Apr 19;7(16):22883-92. doi: 10.18632/oncotarget.8256. Oncotarget. 2016. PMID: 27015362 Free PMC article.
Cytoplasmic localization of the cell polarity factor scribble supports liver tumor formation and tumor cell invasiveness.
Wan S, Meyer AS, Weiler SME, Rupp C, Tóth M, Sticht C, Singer S, Thomann S, Roessler S, Schorpp-Kistner M, Schmitt J, Gretz N, Angel P, Tschaharganeh DF, Marquardt J, Schirmacher P, Pinna F, Breuhahn K. Wan S, et al. Among authors: sticht c. Hepatology. 2018 May;67(5):1842-1856. doi: 10.1002/hep.29669. Epub 2018 Apr 1. Hepatology. 2018. PMID: 29152770
Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p.
Goeppert B, Truckenmueller F, Ori A, Fritz V, Albrecht T, Fraas A, Scherer D, Silos RG, Sticht C, Gretz N, Mehrabi A, Bewerunge-Hudler M, Pusch S, Bermejo JL, Dietrich P, Schirmacher P, Renner M, Roessler S. Goeppert B, et al. Among authors: sticht c. Sci Rep. 2019 Mar 18;9(1):4796. doi: 10.1038/s41598-019-40857-3. Sci Rep. 2019. PMID: 30886199 Free PMC article.
NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.
Luiken S, Fraas A, Bieg M, Sugiyanto R, Goeppert B, Singer S, Ploeger C, Warsow G, Marquardt JU, Sticht C, De La Torre C, Pusch S, Mehrabi A, Gretz N, Schlesner M, Eils R, Schirmacher P, Longerich T, Roessler S. Luiken S, et al. Among authors: sticht c. Oncogene. 2020 Apr;39(15):3128-3144. doi: 10.1038/s41388-020-1198-3. Epub 2020 Feb 13. Oncogene. 2020. PMID: 32055024 Free PMC article.
miRNA profiling of biliary intraepithelial neoplasia reveals stepwise tumorigenesis in distal cholangiocarcinoma via the miR-451a/ATF2 axis.
Loeffler MA, Hu J, Kirchner M, Wei X, Xiao Y, Albrecht T, De La Torre C, Sticht C, Banales JM, Vogel MN, Pathil-Warth A, Mehrabi A, Hoffmann K, Rupp C, Köhler B, Springfeld C, Schirmacher P, Ji J, Roessler S, Goeppert B. Loeffler MA, et al. Among authors: sticht c. J Pathol. 2020 Nov;252(3):239-251. doi: 10.1002/path.5514. Epub 2020 Sep 15. J Pathol. 2020. PMID: 32710569
YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis.
Thomann S, Weiler SME, Marquard S, Rose F, Ball CR, Tóth M, Wei T, Sticht C, Fritzsche S, Roessler S, De La Torre C, Ryschich E, Ermakova O, Mogler C, Kazdal D, Gretz N, Glimm H, Rempel E, Schirmacher P, Breuhahn K. Thomann S, et al. Among authors: sticht c. Cancer Res. 2020 Dec 15;80(24):5502-5514. doi: 10.1158/0008-5472.CAN-20-0242. Epub 2020 Oct 21. Cancer Res. 2020. PMID: 33087321
191 results