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Nasally-delivered interferon-λ protects mice against upper and lower respiratory tract infection of SARS-CoV-2 variants including Omicron.
Chong Z, Karl CE, Halfmann PJ, Kawaoka Y, Winkler ES, Yu J, Diamond MS. Chong Z, et al. Among authors: winkler es. bioRxiv [Preprint]. 2022 Jan 24:2022.01.21.477296. doi: 10.1101/2022.01.21.477296. bioRxiv. 2022. Update in: Cell Rep. 2022 May 10;39(6):110799. doi: 10.1016/j.celrep.2022.110799. PMID: 35118466 Free PMC article. Updated. Preprint.
Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice.
Salazar V, Jagger BW, Mongkolsapaya J, Burgomaster KE, Dejnirattisai W, Winkler ES, Fernandez E, Nelson CA, Fremont DH, Pierson TC, Crowe JE Jr, Screaton GR, Diamond MS. Salazar V, et al. Among authors: winkler es. Cell Rep. 2019 Feb 5;26(6):1585-1597.e4. doi: 10.1016/j.celrep.2019.01.052. Cell Rep. 2019. PMID: 30726740 Free PMC article.
A protective Zika virus E-dimer-based subunit vaccine engineered to abrogate antibody-dependent enhancement of dengue infection.
Slon-Campos JL, Dejnirattisai W, Jagger BW, López-Camacho C, Wongwiwat W, Durnell LA, Winkler ES, Chen RE, Reyes-Sandoval A, Rey FA, Diamond MS, Mongkolsapaya J, Screaton GR. Slon-Campos JL, et al. Among authors: winkler es. Nat Immunol. 2019 Oct;20(10):1291-1298. doi: 10.1038/s41590-019-0477-z. Epub 2019 Sep 2. Nat Immunol. 2019. PMID: 31477918 Free PMC article.
Zika Virus Causes Acute and Chronic Prostatitis in Mice and Macaques.
Halabi J, Jagger BW, Salazar V, Winkler ES, White JP, Humphrey PA, Hirsch AJ, Streblow DN, Diamond MS, Moley K. Halabi J, et al. Among authors: winkler es. J Infect Dis. 2020 Apr 7;221(9):1506-1517. doi: 10.1093/infdis/jiz533. J Infect Dis. 2020. PMID: 31616920 Free PMC article.
Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals.
Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, Martinez DR, Schäfer A, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Zost SJ, et al. Among authors: winkler es. bioRxiv [Preprint]. 2020 May 22:2020.05.22.111005. doi: 10.1101/2020.05.22.111005. bioRxiv. 2020. Update in: Nature. 2020 Aug;584(7821):443-449. doi: 10.1038/s41586-020-2548-6. PMID: 32511409 Free PMC article. Updated. Preprint.
A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies.
Hassan AO, Case JB, Winkler ES, Thackray LB, Kafai NM, Bailey AL, McCune BT, Fox JM, Chen RE, Alsoussi WB, Turner JS, Schmitz AJ, Lei T, Shrihari S, Keeler SP, Fremont DH, Greco S, McCray PB Jr, Perlman S, Holtzman MJ, Ellebedy AH, Diamond MS. Hassan AO, et al. Among authors: winkler es. Cell. 2020 Aug 6;182(3):744-753.e4. doi: 10.1016/j.cell.2020.06.011. Epub 2020 Jun 10. Cell. 2020. PMID: 32553273 Free PMC article.
A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection.
Alsoussi WB, Turner JS, Case JB, Zhao H, Schmitz AJ, Zhou JQ, Chen RE, Lei T, Rizk AA, McIntire KM, Winkler ES, Fox JM, Kafai NM, Thackray LB, Hassan AO, Amanat F, Krammer F, Watson CT, Kleinstein SH, Fremont DH, Diamond MS, Ellebedy AH. Alsoussi WB, et al. Among authors: winkler es. J Immunol. 2020 Aug 15;205(4):915-922. doi: 10.4049/jimmunol.2000583. Epub 2020 Jun 26. J Immunol. 2020. PMID: 32591393 Free PMC article.
The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis.
Winkler ES, Shrihari S, Hykes BL Jr, Handley SA, Andhey PS, Huang YS, Swain A, Droit L, Chebrolu KK, Mack M, Vanlandingham DL, Thackray LB, Cella M, Colonna M, Artyomov MN, Stappenbeck TS, Diamond MS. Winkler ES, et al. Cell. 2020 Aug 20;182(4):901-918.e18. doi: 10.1016/j.cell.2020.06.029. Epub 2020 Jul 14. Cell. 2020. PMID: 32668198 Free PMC article.
47 results