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Randomized clinical trial: A double-blind, proof-of-concept, phase 2 study evaluating the efficacy and safety of vonoprazan 20 or 40 mg versus esomeprazole 40 mg in patients with symptomatic gastro-esophageal reflux disease and partial response to a healing dose of a proton-pump inhibitor.
Tack J, Vladimirov B, Horny I, Chong CF, Eisner J, Czerniak R, Takanami Y. Tack J, et al. Among authors: czerniak r. Neurogastroenterol Motil. 2023 Jan;35(1):e14468. doi: 10.1111/nmo.14468. Epub 2022 Sep 30. Neurogastroenterol Motil. 2023. PMID: 36178335 Clinical Trial.
Pharmacokinetics, Safety, and Tolerability of Vonoprazan- or Esomeprazole-Based Bismuth-Containing Quadruple Therapy: A Phase 1, Double-Blind, Parallel-Group Study in Adults with Helicobacter pylori Infection in China.
Miao J, Hu C, Tang J, Wang W, Wang Y, Men R, Yang L, Gu L, Yoshida N, Czerniak R. Miao J, et al. Among authors: czerniak r. Clin Pharmacol Drug Dev. 2023 Oct;12(10):1036-1044. doi: 10.1002/cpdd.1276. Epub 2023 Jul 13. Clin Pharmacol Drug Dev. 2023. PMID: 37443412 Clinical Trial.
15 results