Liao J - Search Results

1

The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway.

Carlile GW, Yang Q, Matthes E, Liao J, Birault V, Sneddon HF, Poole DL, Hall CJ, Hanrahan JW, Thomas DY. Carlile GW, et al. Among authors: liao j. Sci Rep. 2022 Mar 17;12(1):4595. doi: 10.1038/s41598-022-08661-8. Sci Rep. 2022. PMID: 35302062 Free PMC article.

2

Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect.

Robert R, Carlile GW, Pavel C, Liu N, Anjos SM, Liao J, Luo Y, Zhang D, Thomas DY, Hanrahan JW. Robert R, et al. Among authors: liao j. Mol Pharmacol. 2008 Feb;73(2):478-89. doi: 10.1124/mol.107.040725. Epub 2007 Nov 1. Mol Pharmacol. 2008. PMID: 17975008

3

Correction of the Delta phe508 cystic fibrosis transmembrane conductance regulator trafficking defect by the bioavailable compound glafenine.

Robert R, Carlile GW, Liao J, Balghi H, Lesimple P, Liu N, Kus B, Rotin D, Wilke M, de Jonge HR, Scholte BJ, Thomas DY, Hanrahan JW. Robert R, et al. Among authors: liao j. Mol Pharmacol. 2010 Jun;77(6):922-30. doi: 10.1124/mol.109.062679. Epub 2010 Mar 3. Mol Pharmacol. 2010. PMID: 20200141

4

Identification of a NBD1-binding pharmacological chaperone that corrects the trafficking defect of F508del-CFTR.

Sampson HM, Robert R, Liao J, Matthes E, Carlile GW, Hanrahan JW, Thomas DY. Sampson HM, et al. Among authors: liao j. Chem Biol. 2011 Feb 25;18(2):231-42. doi: 10.1016/j.chembiol.2010.11.016. Chem Biol. 2011. PMID: 21338920

5

Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking.

Carlile GW, Robert R, Goepp J, Matthes E, Liao J, Kus B, Macknight SD, Rotin D, Hanrahan JW, Thomas DY. Carlile GW, et al. Among authors: liao j. J Cyst Fibros. 2015 Jan;14(1):16-25. doi: 10.1016/j.jcf.2014.06.001. Epub 2014 Jun 25. J Cyst Fibros. 2015. PMID: 24974227 Free article.

6

A novel triple combination of pharmacological chaperones improves F508del-CFTR correction.

Carlile GW, Yang Q, Matthes E, Liao J, Radinovic S, Miyamoto C, Robert R, Hanrahan JW, Thomas DY. Carlile GW, et al. Among authors: liao j. Sci Rep. 2018 Jul 30;8(1):11404. doi: 10.1038/s41598-018-29276-y. Sci Rep. 2018. PMID: 30061653 Free PMC article.

7

Phosphorylation of CFTR by PKA promotes binding of the regulatory domain.

Chappe V, Irvine T, Liao J, Evagelidis A, Hanrahan JW. Chappe V, et al. Among authors: liao j. EMBO J. 2005 Aug 3;24(15):2730-40. doi: 10.1038/sj.emboj.7600747. Epub 2005 Jul 7. EMBO J. 2005. PMID: 16001079 Free PMC article.

8

Membrane lateral diffusion and capture of CFTR within transient confinement zones.

Bates IR, Hébert B, Luo Y, Liao J, Bachir AI, Kolin DL, Wiseman PW, Hanrahan JW. Bates IR, et al. Among authors: liao j. Biophys J. 2006 Aug 1;91(3):1046-58. doi: 10.1529/biophysj.106.084830. Epub 2006 May 19. Biophys J. 2006. PMID: 16714353 Free PMC article.

9

Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers.

LeSimple P, Liao J, Robert R, Gruenert DC, Hanrahan JW. LeSimple P, et al. Among authors: liao j. J Physiol. 2010 Apr 15;588(Pt 8):1195-209. doi: 10.1113/jphysiol.2009.182246. Epub 2010 Feb 15. J Physiol. 2010. PMID: 20156845 Free PMC article.

10

Bicarbonate-dependent chloride transport drives fluid secretion by the human airway epithelial cell line Calu-3.

Shan J, Liao J, Huang J, Robert R, Palmer ML, Fahrenkrug SC, O'Grady SM, Hanrahan JW. Shan J, et al. Among authors: liao j. J Physiol. 2012 Nov 1;590(21):5273-97. doi: 10.1113/jphysiol.2012.236893. Epub 2012 Jul 9. J Physiol. 2012. PMID: 22777674 Free PMC article.

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