Li Q - Search Results

1

Epigenetic downregulation of Socs2 contributes to mutant N-Ras-mediated hematopoietic dysregulation.

Jin X, Ng V, Zhao M, Liu L, Higashimoto T, Lee ZH, Chung J, Chen V, Ney G, Kandarpa M, Talpaz M, Li Q. Jin X, et al. Among authors: li q. Dis Model Mech. 2022 May 1;15(5):dmm049088. doi: 10.1242/dmm.049088. Epub 2022 May 6. Dis Model Mech. 2022. PMID: 35352806 Free PMC article.

2

Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness.

Li Q, Bohin N, Wen T, Ng V, Magee J, Chen SC, Shannon K, Morrison SJ. Li Q, et al. Nature. 2013 Dec 5;504(7478):143-147. doi: 10.1038/nature12830. Epub 2013 Nov 27. Nature. 2013. PMID: 24284627 Free PMC article.

3

Preclinical efficacy of MEK inhibition in Nras-mutant AML.

Burgess MR, Hwang E, Firestone AJ, Huang T, Xu J, Zuber J, Bohin N, Wen T, Kogan SC, Haigis KM, Sampath D, Lowe S, Shannon K, Li Q. Burgess MR, et al. Among authors: li q. Blood. 2014 Dec 18;124(26):3947-55. doi: 10.1182/blood-2014-05-574582. Epub 2014 Oct 31. Blood. 2014. PMID: 25361812 Free PMC article.

4

ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response.

Chapple RH, Hu T, Tseng YJ, Liu L, Kitano A, Luu V, Hoegenauer KA, Iwawaki T, Li Q, Nakada D. Chapple RH, et al. Among authors: li q. Elife. 2018 Feb 16;7:e31159. doi: 10.7554/eLife.31159. Elife. 2018. PMID: 29451493 Free PMC article.

5

Oncogenic N-Ras and Tet2 haploinsufficiency collaborate to dysregulate hematopoietic stem and progenitor cells.

Jin X, Qin T, Zhao M, Bailey N, Liu L, Yang K, Ng V, Higashimoto T, Coolon R, Ney G, Figueroa ME, Li Q. Jin X, et al. Among authors: li q. Blood Adv. 2018 Jun 12;2(11):1259-1271. doi: 10.1182/bloodadvances.2018017400. Blood Adv. 2018. PMID: 29866713 Free PMC article.

6

Tsc1 Regulates the Balance Between Osteoblast and Adipocyte Differentiation Through Autophagy/Notch1/β-Catenin Cascade.

Choi HK, Yuan H, Fang F, Wei X, Liu L, Li Q, Guan JL, Liu F. Choi HK, et al. Among authors: li q. J Bone Miner Res. 2018 Nov;33(11):2021-2034. doi: 10.1002/jbmr.3530. Epub 2018 Jul 19. J Bone Miner Res. 2018. PMID: 29924882 Free PMC article.

7

Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells.

Liu L, Zhao M, Jin X, Ney G, Yang KB, Peng F, Cao J, Iwawaki T, Del Valle J, Chen X, Li Q. Liu L, et al. Among authors: li q. Nat Cell Biol. 2019 Mar;21(3):328-337. doi: 10.1038/s41556-019-0285-6. Epub 2019 Feb 18. Nat Cell Biol. 2019. PMID: 30778220 Free PMC article.

8

Mutations predictive of hyperactive Ras signaling correlate with inferior survival across high-risk pediatric acute leukemia.

Ney GM, Anderson B, Bender J, Kumar-Sinha C, Wu YM, Vats P, Cieslik M, Robinson DR, Li Q, Chinnaiyan AM, Mody R. Ney GM, et al. Among authors: li q. Transl Pediatr. 2020 Feb;9(1):43-50. doi: 10.21037/tp.2019.12.03. Transl Pediatr. 2020. PMID: 32154134 Free PMC article.

9

The Emerging Role of Ras Pathway Signaling in Pediatric Cancer.

Ney GM, McKay L, Koschmann C, Mody R, Li Q. Ney GM, et al. Among authors: li q. Cancer Res. 2020 Dec 1;80(23):5155-5163. doi: 10.1158/0008-5472.CAN-20-0916. Epub 2020 Sep 9. Cancer Res. 2020. PMID: 32907837 Free PMC article. Review.

10

ER-associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity.

Liu L, Inoki A, Fan K, Mao F, Shi G, Jin X, Zhao M, Ney G, Jones M, Sun S, Dou Y, Inoki K, Qi L, Li Q. Liu L, et al. Among authors: li q. Blood. 2020 Dec 24;136(26):2975-2986. doi: 10.1182/blood.2020007975. Blood. 2020. PMID: 33150381 Free PMC article.

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