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HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates.
Mak JYW, Wu KC, Gupta PK, Barbero S, McLaughlin MG, Lucke AJ, Tng J, Lim J, Loh Z, Sweet MJ, Reid RC, Liu L, Fairlie DP. Mak JYW, et al. J Med Chem. 2021 Feb 25;64(4):2186-2204. doi: 10.1021/acs.jmedchem.0c01967. Epub 2021 Feb 11. J Med Chem. 2021. PMID: 33570940
MAIT cell-MR1 reactivity is highly conserved across multiple divergent species.
Edmans MD, Connelley TK, Morgan S, Pediongco TJ, Jayaraman S, Juno JA, Meehan BS, Dewar PM, Maze EA, Roos EO, Paudyal B, Mak JYW, Liu L, Fairlie DP, Wang H, Corbett AJ, McCluskey J, Benedictus L, Tchilian E, Klenerman P, Eckle SBG. Edmans MD, et al. Among authors: mak jyw. J Biol Chem. 2024 Jun;300(6):107338. doi: 10.1016/j.jbc.2024.107338. Epub 2024 May 3. J Biol Chem. 2024. PMID: 38705391 Free PMC article.
PAR2 Modulators Derived from GB88.
Yau MK, Liu L, Suen JY, Lim J, Lohman RJ, Jiang Y, Cotterell AJ, Barry GD, Mak JY, Vesey DA, Reid RC, Fairlie DP. Yau MK, et al. ACS Med Chem Lett. 2016 Oct 10;7(12):1179-1184. doi: 10.1021/acsmedchemlett.6b00306. eCollection 2016 Dec 8. ACS Med Chem Lett. 2016. PMID: 27994760 Free PMC article.
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection.
Zhao Z, Wang H, Shi M, Zhu T, Pediongco T, Lim XY, Meehan BS, Nelson AG, Fairlie DP, Mak JYW, Eckle SBG, de Lima Moreira M, Tumpach C, Bramhall M, Williams CG, Lee HJ, Haque A, Evrard M, Rossjohn J, McCluskey J, Corbett AJ, Chen Z. Zhao Z, et al. Among authors: mak jyw. Nat Commun. 2021 Jul 16;12(1):4355. doi: 10.1038/s41467-021-24570-2. Nat Commun. 2021. PMID: 34272362 Free PMC article.
51 results