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Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia.
Pappalardi MB, Keenan K, Cockerill M, Kellner WA, Stowell A, Sherk C, Wong K, Pathuri S, Briand J, Steidel M, Chapman P, Groy A, Wiseman AK, McHugh CF, Campobasso N, Graves AP, Fairweather E, Werner T, Raoof A, Butlin RJ, Rueda L, Horton JR, Fosbenner DT, Zhang C, Handler JL, Muliaditan M, Mebrahtu M, Jaworski JP, McNulty DE, Burt C, Eberl HC, Taylor AN, Ho T, Merrihew S, Foley SW, Rutkowska A, Li M, Romeril SP, Goldberg K, Zhang X, Kershaw CS, Bantscheff M, Jurewicz AJ, Minthorn E, Grandi P, Patel M, Benowitz AB, Mohammad HP, Gilmartin AG, Prinjha RK, Ogilvie D, Carpenter C, Heerding D, Baylin SB, Jones PA, Cheng X, King BW, Luengo JI, Jordan AM, Waddell I, Kruger RG, McCabe MT. Pappalardi MB, et al. Among authors: wong k. Nat Cancer. 2021 Oct;2(10):1002-1017. Epub 2021 Sep 27. Nat Cancer. 2021. PMID: 34790902 Free PMC article.
Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors.
Su DS, Qu J, Schulz M, Blackledge CW, Yu H, Zeng J, Burgess J, Reif A, Stern M, Nagarajan R, Pappalardi MB, Wong K, Graves AP, Bonnette W, Wang L, Elkins P, Knapp-Reed B, Carson JD, McHugh C, Mohammad H, Kruger R, Luengo J, Heerding DA, Creasy CL. Su DS, et al. Among authors: wong k. ACS Med Chem Lett. 2019 Dec 27;11(2):133-140. doi: 10.1021/acsmedchemlett.9b00493. eCollection 2020 Feb 13. ACS Med Chem Lett. 2019. PMID: 32071679 Free PMC article.
Spastic Paresis: A Treatable Movement Disorder.
Gracies JM, Alter KE, Biering-Sørensen B, Dewald JPA, Dressler D, Esquenazi A, Franco JH, Jech R, Kaji R, Jin L, Lim ECH, Raghavan P, Rosales R, Shalash AS, Simpson DM, Suputtitada A, Vecchio M, Wissel J; Spasticity Study Group of the International Parkinson and Movement Disorders Society. Gracies JM, et al. Mov Disord. 2024 Nov 16. doi: 10.1002/mds.30038. Online ahead of print. Mov Disord. 2024. PMID: 39548808 No abstract available.
Exploring the driver events of eccrine poromas and porocarcinomas: A retrospective, cross-institutional study of 54 cases.
Arends MJ, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino JM, Vermes I, Roberts K, Anderson E, van der Horst MPJ, de Saint Aubain N, Alomari AK, Monteagudo C, Billings SD, Frew D, Clarke E, Merchant W, Rajan N, Ferguson P, Mogler C, Ferreira I, Brenn T, van der Weyden L, J Adams D. Arends MJ, et al. Among authors: wong k. Br J Dermatol. 2024 Nov 15:ljae447. doi: 10.1093/bjd/ljae447. Online ahead of print. Br J Dermatol. 2024. PMID: 39546556 No abstract available.
A young girl with a deformed little finger.
Lam PL, Chan CH, Wong D, Wong KC. Lam PL, et al. Among authors: wong kc. Skeletal Radiol. 2024 Nov 15. doi: 10.1007/s00256-024-04822-0. Online ahead of print. Skeletal Radiol. 2024. PMID: 39545943 No abstract available.
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