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Page 1
Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment.
Hu Y, Kirmess KM, Meyer MR, Rabinovici GD, Gatsonis C, Siegel BA, Whitmer RA, Apgar C, Hanna L, Kanekiyo M, Kaplow J, Koyama A, Verbel D, Holubasch MS, Knapik SS, Connor J, Contois JH, Jackson EN, Harpstrite SE, Bateman RJ, Holtzman DM, Verghese PB, Fogelman I, Braunstein JB, Yarasheski KE, West T. Hu Y, et al. Among authors: yarasheski ke. JAMA Netw Open. 2022 Apr 1;5(4):e228392. doi: 10.1001/jamanetworkopen.2022.8392. JAMA Netw Open. 2022. PMID: 35446396 Free PMC article.
Decreased clearance of CNS beta-amyloid in Alzheimer's disease.
Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, Yarasheski KE, Bateman RJ. Mawuenyega KG, et al. Among authors: yarasheski ke. Science. 2010 Dec 24;330(6012):1774. doi: 10.1126/science.1197623. Epub 2010 Dec 9. Science. 2010. PMID: 21148344 Free PMC article.
In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.
Wildsmith KR, Basak JM, Patterson BW, Pyatkivskyy Y, Kim J, Yarasheski KE, Wang JX, Mawuenyega KG, Jiang H, Parsadanian M, Yoon H, Kasten T, Sigurdson WC, Xiong C, Goate A, Holtzman DM, Bateman RJ. Wildsmith KR, et al. Among authors: yarasheski ke. PLoS One. 2012;7(6):e38013. doi: 10.1371/journal.pone.0038013. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675504 Free PMC article.
Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers.
Potter R, Patterson BW, Elbert DL, Ovod V, Kasten T, Sigurdson W, Mawuenyega K, Blazey T, Goate A, Chott R, Yarasheski KE, Holtzman DM, Morris JC, Benzinger TL, Bateman RJ. Potter R, et al. Among authors: yarasheski ke. Sci Transl Med. 2013 Jun 12;5(189):189ra77. doi: 10.1126/scitranslmed.3005615. Sci Transl Med. 2013. PMID: 23761040 Free PMC article.
An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice.
Sheline YI, West T, Yarasheski K, Swarm R, Jasielec MS, Fisher JR, Ficker WD, Yan P, Xiong C, Frederiksen C, Grzelak MV, Chott R, Bateman RJ, Morris JC, Mintun MA, Lee JM, Cirrito JR. Sheline YI, et al. Sci Transl Med. 2014 May 14;6(236):236re4. doi: 10.1126/scitranslmed.3008169. Sci Transl Med. 2014. PMID: 24828079 Free PMC article. Clinical Trial.
CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition.
Dobrowolska JA, Michener MS, Wu G, Patterson BW, Chott R, Ovod V, Pyatkivskyy Y, Wildsmith KR, Kasten T, Mathers P, Dancho M, Lennox C, Smith BE, Gilberto D, McLoughlin D, Holder DJ, Stamford AW, Yarasheski KE, Kennedy ME, Savage MJ, Bateman RJ. Dobrowolska JA, et al. Among authors: yarasheski ke. J Neurosci. 2014 Jun 11;34(24):8336-46. doi: 10.1523/JNEUROSCI.0540-14.2014. J Neurosci. 2014. PMID: 24920637 Free PMC article.
180 results