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Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion.
Georgiadou E, Muralidharan C, Martinez M, Chabosseau P, Akalestou E, Tomas A, Wern FYS, Stylianides T, Wretlind A, Legido-Quigley C, Jones B, Lopez-Noriega L, Xu Y, Gu G, Alsabeeh N, Cruciani-Guglielmacci C, Magnan C, Ibberson M, Leclerc I, Ali Y, Soleimanpour SA, Linnemann AK, Rodriguez TA, Rutter GA. Georgiadou E, et al. Among authors: leclerc i. Diabetes. 2022 Jul 1;71(7):1472-1489. doi: 10.2337/db21-0800. Diabetes. 2022. PMID: 35472764 Free PMC article.
5'-AMP-activated protein kinase controls insulin-containing secretory vesicle dynamics.
Tsuboi T, da Silva Xavier G, Leclerc I, Rutter GA. Tsuboi T, et al. Among authors: leclerc i. J Biol Chem. 2003 Dec 26;278(52):52042-51. doi: 10.1074/jbc.M307800200. Epub 2003 Oct 7. J Biol Chem. 2003. PMID: 14532293 Free article.
Changes in 5'-AMP-activated protein kinase (AMPK) activity have recently been implicated in the control of insulin secretion by glucose (da Silva Xavier, G., Leclerc, I., Varadi, A., Tsuboi, T., Moule, S. K., and Rutter, G. A. (2003) Biochem. J. 371, 761-774). ...
Changes in 5'-AMP-activated protein kinase (AMPK) activity have recently been implicated in the control of insulin secretion by glucose (da …
Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).
Diraison F, Parton L, Ferré P, Foufelle F, Briscoe CP, Leclerc I, Rutter GA. Diraison F, et al. Among authors: leclerc i. Biochem J. 2004 Mar 15;378(Pt 3):769-78. doi: 10.1042/BJ20031277. Biochem J. 2004. PMID: 14690455 Free PMC article.
Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion.
Leclerc I, Woltersdorf WW, da Silva Xavier G, Rowe RL, Cross SE, Korbutt GS, Rajotte RV, Smith R, Rutter GA. Leclerc I, et al. Am J Physiol Endocrinol Metab. 2004 Jun;286(6):E1023-31. doi: 10.1152/ajpendo.00532.2003. Epub 2004 Feb 10. Am J Physiol Endocrinol Metab. 2004. PMID: 14871885 Free article.
We have recently shown that forced increases in AMPK activity inhibit insulin secretion from MIN6 cells (da Silva Xavier G, Leclerc I, Varadi A, Tsuboi T, Moule SK, and Rutter GA. Biochem J 371: 761-774, 2003). ...
We have recently shown that forced increases in AMPK activity inhibit insulin secretion from MIN6 cells (da Silva Xavier G, Leclerc
66 results