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Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species.
Doan MT, Neinast MD, Varner EL, Bedi KC Jr, Bartee D, Jiang H, Trefely S, Xu P, Singh JP, Jang C, Rame JE, Brady DC, Meier JL, Marguiles KB, Arany Z, Snyder NW. Doan MT, et al. Among authors: jiang h. J Lipid Res. 2022 Jun;63(6):100224. doi: 10.1016/j.jlr.2022.100224. Epub 2022 May 11. J Lipid Res. 2022. PMID: 35568254 Free PMC article.
Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation.
Trefely S, Huber K, Liu J, Noji M, Stransky S, Singh J, Doan MT, Lovell CD, von Krusenstiern E, Jiang H, Bostwick A, Pepper HL, Izzo L, Zhao S, Xu JP, Bedi KC Jr, Rame JE, Bogner-Strauss JG, Mesaros C, Sidoli S, Wellen KE, Snyder NW. Trefely S, et al. Among authors: jiang h. Mol Cell. 2022 Jan 20;82(2):447-462.e6. doi: 10.1016/j.molcel.2021.11.006. Epub 2021 Dec 1. Mol Cell. 2022. PMID: 34856123 Free PMC article.
Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy.
Kopinski PK, Janssen KA, Schaefer PM, Trefely S, Perry CE, Potluri P, Tintos-Hernandez JA, Singh LN, Karch KR, Campbell SL, Doan MT, Jiang H, Nissim I, Nakamaru-Ogiso E, Wellen KE, Snyder NW, Garcia BA, Wallace DC. Kopinski PK, et al. Among authors: jiang h. Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):16028-16035. doi: 10.1073/pnas.1906896116. Epub 2019 Jun 28. Proc Natl Acad Sci U S A. 2019. PMID: 31253706 Free PMC article.
Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses.
Langston PK, Nambu A, Jung J, Shibata M, Aksoylar HI, Lei J, Xu P, Doan MT, Jiang H, MacArthur MR, Gao X, Kong Y, Chouchani ET, Locasale JW, Snyder NW, Horng T. Langston PK, et al. Among authors: jiang h. Nat Immunol. 2019 Sep;20(9):1186-1195. doi: 10.1038/s41590-019-0453-7. Epub 2019 Aug 5. Nat Immunol. 2019. PMID: 31384058 Free PMC article.
Artefactual formation of pyruvate from in-source conversion of lactate.
Trefely S, Mesaros C, Xu P, Doan MT, Jiang H, Altinok O, Orynbayeva Z, Snyder NW. Trefely S, et al. Among authors: jiang h. Rapid Commun Mass Spectrom. 2018 May 8:10.1002/rcm.8159. doi: 10.1002/rcm.8159. Online ahead of print. Rapid Commun Mass Spectrom. 2018. PMID: 29740888 Free PMC article.
Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming.
Buj R, Chen CW, Dahl ES, Leon KE, Kuskovsky R, Maglakelidze N, Navaratnarajah M, Zhang G, Doan MT, Jiang H, Zaleski M, Kutzler L, Lacko H, Lu Y, Mills GB, Gowda R, Robertson GP, Warrick JI, Herlyn M, Imamura Y, Kimball SR, DeGraff DJ, Snyder NW, Aird KM. Buj R, et al. Among authors: jiang h. Cell Rep. 2019 Aug 20;28(8):1971-1980.e8. doi: 10.1016/j.celrep.2019.07.084. Cell Rep. 2019. PMID: 31433975 Free PMC article.
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