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mRNA-1273 and Ad26.COV2.S vaccines protect against the B.1.621 variant of SARS-CoV-2.
Darling TL, Ying B, Whitener B, VanBlargan LA, Bricker TL, Liang CY, Joshi A, Bamunuarachchi G, Seehra K, Schmitz AJ, Halfmann PJ, Kawaoka Y, Elbashir SM, Edwards DK, Thackray LB, Diamond MS, Boon ACM. Darling TL, et al. Among authors: seehra k. Med. 2022 May 13;3(5):309-324.e6. doi: 10.1016/j.medj.2022.03.009. Epub 2022 Apr 15. Med. 2022. PMID: 35584653 Free PMC article.
The Highly Conserved Stem-Loop II Motif Is Dispensable for SARS-CoV-2.
Jiang H, Joshi A, Gan T, Janowski AB, Fujii C, Bricker TL, Darling TL, Harastani HH, Seehra K, Chen H, Tahan S, Jung A, Febles B, Blatter JA, Handley SA, Parikh BA, Wang D, Boon ACM. Jiang H, et al. Among authors: seehra k. J Virol. 2023 Jun 29;97(6):e0063523. doi: 10.1128/jvi.00635-23. Epub 2023 May 18. J Virol. 2023. PMID: 37223945 Free PMC article.
An immunostimulatory glycolipid that blocks SARS-CoV-2, RSV, and influenza infections in vivo.
Tsuji M, Nair MS, Masuda K, Castagna C, Chong Z, Darling TL, Seehra K, Hwang Y, Ribeiro ÁL, Ferreira GM, Corredor L, Coelho-Dos-Reis JGA, Tsuji Y, Mori M, Boon ACM, Diamond MS, Huang Y, Ho DD. Tsuji M, et al. Among authors: seehra k. Nat Commun. 2023 Jul 5;14(1):3959. doi: 10.1038/s41467-023-39738-1. Nat Commun. 2023. PMID: 37402814 Free PMC article.
Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer.
Bulle A, Liu P, Seehra K, Bansod S, Chen Y, Zahra K, Somani V, Khawar IA, Chen HP, Dodhiawala PB, Li L, Geng Y, Mo CK, Mahsl J, Ding L, Govindan R, Davies S, Mudd J, Hawkins WG, Fields RC, DeNardo DG, Knoerzer D, Held JM, Grierson PM, Wang-Gillam A, Ruzinova MB, Lim KH. Bulle A, et al. Among authors: seehra k. Nat Commun. 2024 Mar 20;15(1):2503. doi: 10.1038/s41467-024-46811-w. Nat Commun. 2024. PMID: 38509064 Free PMC article.
Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters.
Boon J, Soudani N, Bricker T, Darling T, Seehra K, Patel N, Guebre-Xabier M, Smith G, Suthar M, Ellebedy A, Davis-Gardner M. Boon J, et al. Among authors: seehra k. Res Sq [Preprint]. 2024 Feb 9:rs.3.rs-3873514. doi: 10.21203/rs.3.rs-3873514/v1. Res Sq. 2024. Update in: J Virol. 2024 Oct 22;98(10):e0052824. doi: 10.1128/jvi.00528-24. PMID: 38405749 Free PMC article. Updated. Preprint.
The highly conserved stem-loop II motif is dispensable for SARS-CoV-2.
Jiang H, Joshi A, Gan T, Janowski AB, Fujii C, Bricker TL, Darling TL, Harastani HH, Seehra K, Chen H, Tahan S, Jung A, Febles B, Blatter JA, Handley SA, Parikh BA, Wang D, Boon AC. Jiang H, et al. Among authors: seehra k. bioRxiv [Preprint]. 2023 Mar 16:2023.03.15.532878. doi: 10.1101/2023.03.15.532878. bioRxiv. 2023. Update in: J Virol. 2023 Jun 29;97(6):e0063523. doi: 10.1128/jvi.00635-23. PMID: 36993345 Free PMC article. Updated. Preprint.
The highly conserved stem-loop II motif is important for the lifecycle of astroviruses but dispensable for SARS-CoV-2.
Janowski AB, Jiang H, Fujii C, Owen MC, Bricker TL, Darling TL, Harastani HH, Seehra K, Tahan S, Jung A, Febles B, Blatter JA, Handley SA, Parikh BA, Lulla V, Boon AC, Wang D. Janowski AB, et al. Among authors: seehra k. bioRxiv [Preprint]. 2022 May 2:2022.04.30.486882. doi: 10.1101/2022.04.30.486882. bioRxiv. 2022. Update in: J Virol. 2023 Jun 29;97(6):e0063523. doi: 10.1128/jvi.00635-23. PMID: 35547847 Free PMC article. Updated. Preprint.
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