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Molecular mechanism of the wake-promoting agent TAK-925.
Yin J, Kang Y, McGrath AP, Chapman K, Sjodt M, Kimura E, Okabe A, Koike T, Miyanohana Y, Shimizu Y, Rallabandi R, Lian P, Bai X, Flinspach M, De Brabander JK, Rosenbaum DM. Yin J, et al. Among authors: kang y. Nat Commun. 2022 May 25;13(1):2902. doi: 10.1038/s41467-022-30601-3. Nat Commun. 2022. PMID: 35614071 Free PMC article.
Reply to: The G protein preference of orexin receptors is currently an unresolved issue.
Yin J, Kang Y, McGrath AP, Chapman K, Sjodt M, Kimura E, Okabe A, Koike T, Miyanohana Y, Shimizu Y, Rallabandi R, Lian P, Bai X, Flinspach M, De Brabander JK, Rosenbaum DM. Yin J, et al. Among authors: kang y. Nat Commun. 2023 Jun 1;14(1):3163. doi: 10.1038/s41467-023-38765-2. Nat Commun. 2023. PMID: 37264001 Free PMC article. No abstract available.
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Kang Y, Kuybeda O, de Waal PW, Mukherjee S, Van Eps N, Dutka P, Zhou XE, Bartesaghi A, Erramilli S, Morizumi T, Gu X, Yin Y, Liu P, Jiang Y, Meng X, Zhao G, Melcher K, Ernst OP, Kossiakoff AA, Subramaniam S, Xu HE. Kang Y, et al. Nature. 2018 Jun;558(7711):553-558. doi: 10.1038/s41586-018-0215-y. Epub 2018 Jun 13. Nature. 2018. PMID: 29899450 Free PMC article.
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Mukherjee S, Erramilli SK, Ammirati M, Alvarez FJD, Fennell KF, Purdy MD, Skrobek BM, Radziwon K, Coukos J, Kang Y, Dutka P, Gao X, Qiu X, Yeager M, Eric Xu H, Han S, Kossiakoff AA. Mukherjee S, et al. Among authors: kang y. Nat Commun. 2020 Mar 27;11(1):1598. doi: 10.1038/s41467-020-15363-0. Nat Commun. 2020. PMID: 32221310 Free PMC article.
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE. Kang Y, et al. Nature. 2015 Jul 30;523(7562):561-7. doi: 10.1038/nature14656. Epub 2015 Jul 22. Nature. 2015. PMID: 26200343 Free PMC article.
Structure and dynamics of the active human parathyroid hormone receptor-1.
Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, Li C, Jiang Y, Watanabe T, Gardella TJ, Melcher K, Wang MW, Vilardaga JP, Xu HE, Zhang Y. Zhao LH, et al. Among authors: kang y. Science. 2019 Apr 12;364(6436):148-153. doi: 10.1126/science.aav7942. Science. 2019. PMID: 30975883 Free PMC article.
A structural snapshot of the rhodopsin-arrestin complex.
Kang Y, Gao X, Zhou XE, He Y, Melcher K, Xu HE. Kang Y, et al. FEBS J. 2016 Mar;283(5):816-21. doi: 10.1111/febs.13561. Epub 2015 Nov 7. FEBS J. 2016. PMID: 26467309 Free PMC article. Review.
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