Telenius JM - Search Results

1

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin.

Truch J, Downes DJ, Scott C, Gür ER, Telenius JM, Repapi E, Schwessinger R, Gosden M, Brown JM, Taylor S, Cheong PL, Hughes JR, Higgs DR, Gibbons RJ. Truch J, et al. Among authors: telenius jm. Nat Commun. 2022 Jun 17;13(1):3485. doi: 10.1038/s41467-022-31194-7. Nat Commun. 2022. PMID: 35710802 Free PMC article.

2

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.

Mettananda S, Fisher CA, Hay D, Badat M, Quek L, Clark K, Hublitz P, Downes D, Kerry J, Gosden M, Telenius J, Sloane-Stanley JA, Faustino P, Coelho A, Doondeea J, Usukhbayar B, Sopp P, Sharpe JA, Hughes JR, Vyas P, Gibbons RJ, Higgs DR. Mettananda S, et al. Nat Commun. 2017 Sep 4;8(1):424. doi: 10.1038/s41467-017-00479-7. Nat Commun. 2017. PMID: 28871148 Free PMC article.

3

How to Tackle Challenging ChIP-Seq, with Long-Range Cross-Linking, Using ATRX as an Example.

Truch J, Telenius J, Higgs DR, Gibbons RJ. Truch J, et al. Methods Mol Biol. 2018;1832:105-130. doi: 10.1007/978-1-4939-8663-7_6. Methods Mol Biol. 2018. PMID: 30073524

4

High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale.

Downes DJ, Beagrie RA, Gosden ME, Telenius J, Carpenter SJ, Nussbaum L, De Ornellas S, Sergeant M, Eijsbouts CQ, Schwessinger R, Kerry J, Roberts N, Shivalingam A, El-Sagheer A, Oudelaar AM, Brown T, Buckle VJ, Davies JOJ, Hughes JR. Downes DJ, et al. Nat Commun. 2021 Jan 22;12(1):531. doi: 10.1038/s41467-020-20809-6. Nat Commun. 2021. PMID: 33483495 Free PMC article.

5

A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker.

Bozhilov YK, Downes DJ, Telenius J, Marieke Oudelaar A, Olivier EN, Mountford JC, Hughes JR, Gibbons RJ, Higgs DR. Bozhilov YK, et al. Nat Commun. 2021 Jun 21;12(1):3806. doi: 10.1038/s41467-021-23980-6. Nat Commun. 2021. PMID: 34155213 Free PMC article.

6

Reactivation of a developmentally silenced embryonic globin gene.

King AJ, Songdej D, Downes DJ, Beagrie RA, Liu S, Buckley M, Hua P, Suciu MC, Marieke Oudelaar A, Hanssen LLP, Jeziorska D, Roberts N, Carpenter SJ, Francis H, Telenius J, Olijnik AA, Sharpe JA, Sloane-Stanley J, Eglinton J, Kassouf MT, Orkin SH, Pennacchio LA, Davies JOJ, Hughes JR, Higgs DR, Babbs C. King AJ, et al. Nat Commun. 2021 Jul 21;12(1):4439. doi: 10.1038/s41467-021-24402-3. Nat Commun. 2021. PMID: 34290235 Free PMC article.

7

Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development.

Owens DDG, Anselmi G, Oudelaar AM, Downes DJ, Cavallo A, Harman JR, Schwessinger R, Bucakci A, Greder L, de Ornellas S, Jeziorska D, Telenius J, Hughes JR, de Bruijn MFTR. Owens DDG, et al. Nat Commun. 2022 Feb 9;13(1):773. doi: 10.1038/s41467-022-28376-8. Nat Commun. 2022. PMID: 35140205 Free PMC article.

8

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.

Brown JM, Roberts NA, Graham B, Waithe D, Lagerholm C, Telenius JM, De Ornellas S, Oudelaar AM, Scott C, Szczerbal I, Babbs C, Kassouf MT, Hughes JR, Higgs DR, Buckle VJ. Brown JM, et al. Among authors: telenius jm. Nat Commun. 2018 Sep 21;9(1):3849. doi: 10.1038/s41467-018-06248-4. Nat Commun. 2018. PMID: 30242161 Free PMC article.

9

A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus.

Oudelaar AM, Harrold CL, Hanssen LLP, Telenius JM, Higgs DR, Hughes JR. Oudelaar AM, et al. Among authors: telenius jm. Nat Commun. 2019 Nov 27;10(1):5412. doi: 10.1038/s41467-019-13404-x. Nat Commun. 2019. PMID: 31776347 Free PMC article.

10

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.

Godfrey L, Crump NT, Thorne R, Lau IJ, Repapi E, Dimou D, Smith AL, Harman JR, Telenius JM, Oudelaar AM, Downes DJ, Vyas P, Hughes JR, Milne TA. Godfrey L, et al. Among authors: telenius jm. Nat Commun. 2019 Jun 26;10(1):2803. doi: 10.1038/s41467-019-10844-3. Nat Commun. 2019. PMID: 31243293 Free PMC article.

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