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A Phase 1 Proof of Concept Study Evaluating the Addition of an LSD1 Inhibitor to Nab-Paclitaxel in Advanced or Metastatic Breast Cancer (EPI-PRIMED).
Prasanna T, Malik L, McCuaig RD, Tu WJ, Wu F, Lim PS, Tan AHY, Dahlstrom JE, Clingan P, Moylan E, Chrisp J, Fuller D, Rao S, Yip D. Prasanna T, et al. Among authors: mccuaig rd. Front Oncol. 2022 Jun 3;12:862427. doi: 10.3389/fonc.2022.862427. eCollection 2022. Front Oncol. 2022. PMID: 35719960 Free PMC article.
Chromatinized Protein Kinase C-θ: Can It Escape the Clutches of NF-κB?
Sutcliffe EL, Li J, Zafar A, Hardy K, Ghildyal R, McCuaig R, Norris NC, Lim PS, Milburn PJ, Casarotto MG, Denyer G, Rao S. Sutcliffe EL, et al. Front Immunol. 2012 Aug 28;3:260. doi: 10.3389/fimmu.2012.00260. eCollection 2012. Front Immunol. 2012. PMID: 22969762 Free PMC article.
Chromatinized protein kinase C-θ directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells.
Zafar A, Wu F, Hardy K, Li J, Tu WJ, McCuaig R, Harris J, Khanna KK, Attema J, Gregory PA, Goodall GJ, Harrington K, Dahlstrom JE, Boulding T, Madden R, Tan A, Milburn PJ, Rao S. Zafar A, et al. Mol Cell Biol. 2014 Aug;34(16):2961-80. doi: 10.1128/MCB.01693-13. Epub 2014 Jun 2. Mol Cell Biol. 2014. PMID: 24891615 Free PMC article.
Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation.
Li J, Hardy K, Phetsouphanh C, Tu WJ, Sutcliffe EL, McCuaig R, Sutton CR, Zafar A, Munier CM, Zaunders JJ, Xu Y, Theodoratos A, Tan A, Lim PS, Knaute T, Masch A, Zerweck J, Brezar V, Milburn PJ, Dunn J, Casarotto MG, Turner SJ, Seddiki N, Kelleher AD, Rao S. Li J, et al. J Cell Sci. 2016 Jun 15;129(12):2448-61. doi: 10.1242/jcs.181248. Epub 2016 May 5. J Cell Sci. 2016. PMID: 27149922 Free PMC article.
24 results