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A Phase 1 Proof of Concept Study Evaluating the Addition of an LSD1 Inhibitor to Nab-Paclitaxel in Advanced or Metastatic Breast Cancer (EPI-PRIMED).
Prasanna T, Malik L, McCuaig RD, Tu WJ, Wu F, Lim PS, Tan AHY, Dahlstrom JE, Clingan P, Moylan E, Chrisp J, Fuller D, Rao S, Yip D. Prasanna T, et al. Among authors: wu f. Front Oncol. 2022 Jun 3;12:862427. doi: 10.3389/fonc.2022.862427. eCollection 2022. Front Oncol. 2022. PMID: 35719960 Free PMC article.
Selective Targeting of Protein Kinase C (PKC)-θ Nuclear Translocation Reduces Mesenchymal Gene Signatures and Reinvigorates Dysfunctional CD8+ T Cells in Immunotherapy-Resistant and Metastatic Cancers.
Dunn J, McCuaig RD, Tan AHY, Tu WJ, Wu F, Wagstaff KM, Zafar A, Ali S, Diwakar H, Dahlstrom JE, Bean EG, Forwood JK, Tsimbalyuk S, Cross EM, Hardy K, Bain AL, Ahern E, Dolcetti R, Mazzieri R, Yip D, Eastgate M, Malik L, Milburn P, Jans DA, Rao S. Dunn J, et al. Among authors: wu f. Cancers (Basel). 2022 Mar 21;14(6):1596. doi: 10.3390/cancers14061596. Cancers (Basel). 2022. PMID: 35326747 Free PMC article.
Chromatinized protein kinase C-θ directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells.
Zafar A, Wu F, Hardy K, Li J, Tu WJ, McCuaig R, Harris J, Khanna KK, Attema J, Gregory PA, Goodall GJ, Harrington K, Dahlstrom JE, Boulding T, Madden R, Tan A, Milburn PJ, Rao S. Zafar A, et al. Among authors: wu f. Mol Cell Biol. 2014 Aug;34(16):2961-80. doi: 10.1128/MCB.01693-13. Epub 2014 Jun 2. Mol Cell Biol. 2014. PMID: 24891615 Free PMC article.
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