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Page 1
Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH.
Hendrikx T, Porsch F, Kiss MG, Rajcic D, Papac-Miličević N, Hoebinger C, Goederle L, Hladik A, Shaw LE, Horstmann H, Knapp S, Derdak S, Bilban M, Heintz L, Krawczyk M, Paternostro R, Trauner M, Farlik M, Wolf D, Binder CJ. Hendrikx T, et al. Among authors: goederle l. J Hepatol. 2022 Nov;77(5):1373-1385. doi: 10.1016/j.jhep.2022.06.004. Epub 2022 Jun 21. J Hepatol. 2022. PMID: 35750138 Free article.
Pharmacological inhibition of fatty acid oxidation reduces atherosclerosis progression by suppression of macrophage NLRP3 inflammasome activation.
Hohensinner PJ, Lenz M, Haider P, Mayer J, Richter M, Kaun C, Goederle L, Brekalo M, Salzmann M, Sharma S, Fischer MB, Stojkovic S, Ramsmayer D, Hengstenberg C, Podesser BK, Huber K, Binder CJ, Wojta J, Speidl WS. Hohensinner PJ, et al. Among authors: goederle l. Biochem Pharmacol. 2021 Aug;190:114634. doi: 10.1016/j.bcp.2021.114634. Epub 2021 May 28. Biochem Pharmacol. 2021. PMID: 34058186 Free article.
Pharmacologic modulation of intracellular Na+ concentration with ranolazine impacts inflammatory response in humans and mice.
Lenz M, Salzmann M, Ciotu CI, Kaun C, Krychtiuk KA, Rehberger Likozar A, Sebestjen M, Goederle L, Rauscher S, Krivaja Z, Binder CJ, Huber K, Hengstenberg C, Podesser BK, Fischer MJM, Wojta J, Hohensinner PJ, Speidl WS. Lenz M, et al. Among authors: goederle l. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2207020119. doi: 10.1073/pnas.2207020119. Epub 2022 Jul 13. Proc Natl Acad Sci U S A. 2022. PMID: 35858345 Free PMC article.