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Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH.
Hendrikx T, Porsch F, Kiss MG, Rajcic D, Papac-Miličević N, Hoebinger C, Goederle L, Hladik A, Shaw LE, Horstmann H, Knapp S, Derdak S, Bilban M, Heintz L, Krawczyk M, Paternostro R, Trauner M, Farlik M, Wolf D, Binder CJ. Hendrikx T, et al. J Hepatol. 2022 Nov;77(5):1373-1385. doi: 10.1016/j.jhep.2022.06.004. Epub 2022 Jun 21. J Hepatol. 2022. PMID: 35750138 Free article.
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease.
Bieghs V, Van Gorp PJ, Wouters K, Hendrikx T, Gijbels MJ, van Bilsen M, Bakker J, Binder CJ, Lütjohann D, Staels B, Hofker MH, Shiri-Sverdlov R. Bieghs V, et al. Among authors: hendrikx t. PLoS One. 2012;7(1):e30668. doi: 10.1371/journal.pone.0030668. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295101 Free PMC article.
Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice.
Hendrikx T, Bieghs V, Walenbergh SM, van Gorp PJ, Verheyen F, Jeurissen ML, Steinbusch MM, Vaes N, Binder CJ, Koek GH, Stienstra R, Netea MG, Hofker MH, Shiri-Sverdlov R. Hendrikx T, et al. PLoS One. 2013 Dec 2;8(12):e78792. doi: 10.1371/journal.pone.0078792. eCollection 2013. PLoS One. 2013. PMID: 24312444 Free PMC article.
Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells.
Gruber S, Hendrikx T, Tsiantoulas D, Ozsvar-Kozma M, Göderle L, Mallat Z, Witztum JL, Shiri-Sverdlov R, Nitschke L, Binder CJ. Gruber S, et al. Among authors: hendrikx t. Cell Rep. 2016 Mar 15;14(10):2348-61. doi: 10.1016/j.celrep.2016.02.027. Epub 2016 Mar 3. Cell Rep. 2016. PMID: 26947073 Free PMC article.
71 results