Watari K - Search Results

1

Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling.

Xian H, Watari K, Sanchez-Lopez E, Offenberger J, Onyuru J, Sampath H, Ying W, Hoffman HM, Shadel GS, Karin M. Xian H, et al. Among authors: watari k. Immunity. 2022 Aug 9;55(8):1370-1385.e8. doi: 10.1016/j.immuni.2022.06.007. Epub 2022 Jul 13. Immunity. 2022. PMID: 35835107 Free PMC article.

2

AXL/CDCP1/SRC axis confers acquired resistance to osimertinib in lung cancer.

Murakami Y, Kusakabe D, Watari K, Kawahara A, Azuma K, Akiba J, Taniguchi M, Kuwano M, Ono M. Murakami Y, et al. Among authors: watari k. Sci Rep. 2022 May 28;12(1):8983. doi: 10.1038/s41598-022-12995-8. Sci Rep. 2022. PMID: 35643725 Free PMC article.

3

Erlotinib resistance in lung cancer cells mediated by integrin β1/Src/Akt-driven bypass signaling.

Kanda R, Kawahara A, Watari K, Murakami Y, Sonoda K, Maeda M, Fujita H, Kage M, Uramoto H, Costa C, Kuwano M, Ono M. Kanda R, et al. Among authors: watari k. Cancer Res. 2013 Oct 15;73(20):6243-53. doi: 10.1158/0008-5472.CAN-12-4502. Epub 2013 Jul 19. Cancer Res. 2013. PMID: 23872583

4

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor.

Azuma K, Kawahara A, Sonoda K, Nakashima K, Tashiro K, Watari K, Izumi H, Kage M, Kuwano M, Ono M, Hoshino T. Azuma K, et al. Among authors: watari k. Oncotarget. 2014 Aug 15;5(15):5908-19. doi: 10.18632/oncotarget.1866. Oncotarget. 2014. PMID: 25115383 Free PMC article.

5

CpG hypermethylation contributes to decreased expression of PTEN during acquired resistance to gefitinib in human lung cancer cell lines.

Maeda M, Murakami Y, Watari K, Kuwano M, Izumi H, Ono M. Maeda M, et al. Among authors: watari k. Lung Cancer. 2015 Mar;87(3):265-71. doi: 10.1016/j.lungcan.2015.01.009. Epub 2015 Jan 20. Lung Cancer. 2015. PMID: 25638724

6

Overcoming drug resistance to receptor tyrosine kinase inhibitors: Learning from lung cancer.

Kuwano M, Sonoda K, Murakami Y, Watari K, Ono M. Kuwano M, et al. Among authors: watari k. Pharmacol Ther. 2016 May;161:97-110. doi: 10.1016/j.pharmthera.2016.03.002. Epub 2016 Mar 18. Pharmacol Ther. 2016. PMID: 27000770 Review.

7

The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells.

Murakami Y, Sonoda K, Abe H, Watari K, Kusakabe D, Azuma K, Kawahara A, Akiba J, Oneyama C, Pachter JA, Sakai K, Nishio K, Kuwano M, Ono M. Murakami Y, et al. Among authors: watari k. Oncotarget. 2017 Aug 7;8(41):70736-70751. doi: 10.18632/oncotarget.19982. eCollection 2017 Sep 19. Oncotarget. 2017. PMID: 29050315 Free PMC article.

8

Infiltration of thymidine phosphorylase-positive macrophages is closely associated with tumor angiogenesis and survival in intestinal type gastric cancer.

Kawahara A, Hattori S, Akiba J, Nakashima K, Taira T, Watari K, Hosoi F, Uba M, Basaki Y, Koufuji K, Shirouzu K, Akiyama S, Kuwano M, Kage M, Ono M. Kawahara A, et al. Among authors: watari k. Oncol Rep. 2010 Aug;24(2):405-15. doi: 10.3892/or_00000873. Oncol Rep. 2010. PMID: 20596627

9

N-myc downstream regulated gene1/Cap43 overexpression suppresses tumor growth by hepatic cancer cells through cell cycle arrest at the G0/G1 phase.

Akiba J, Murakami Y, Noda M, Watari K, Ogasawara S, Yoshida T, Kawahara A, Sanada S, Yasumoto M, Yamaguchi R, Kage M, Kuwano M, Ono M, Yano H. Akiba J, et al. Among authors: watari k. Cancer Lett. 2011 Nov 1;310(1):25-34. doi: 10.1016/j.canlet.2011.05.034. Epub 2011 Jun 24. Cancer Lett. 2011. PMID: 21775055

10

The antitumor effect of a novel angiogenesis inhibitor (an octahydronaphthalene derivative) targeting both VEGF receptor and NF-κB pathway.

Watari K, Nakamura M, Fukunaga Y, Furuno A, Shibata T, Kawahara A, Hosoi F, Kuwano T, Kuwano M, Ono M. Watari K, et al. Int J Cancer. 2012 Jul 15;131(2):310-21. doi: 10.1002/ijc.26356. Epub 2011 Sep 14. Int J Cancer. 2012. PMID: 21826646

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