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Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis.
Weindel CG, Martinez EL, Zhao X, Mabry CJ, Bell SL, Vail KJ, Coleman AK, VanPortfliet JJ, Zhao B, Wagner AR, Azam S, Scott HM, Li P, West AP, Karpac J, Patrick KL, Watson RO. Weindel CG, et al. Among authors: west ap. Cell. 2022 Aug 18;185(17):3214-3231.e23. doi: 10.1016/j.cell.2022.06.038. Epub 2022 Jul 30. Cell. 2022. PMID: 35907404 Free PMC article.
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Zhao B, Du F, Xu P, Shu C, Sankaran B, Bell SL, Liu M, Lei Y, Gao X, Fu X, Zhu F, Liu Y, Laganowsky A, Zheng X, Ji JY, West AP, Watson RO, Li P. Zhao B, et al. Among authors: west ap. Nature. 2019 May;569(7758):718-722. doi: 10.1038/s41586-019-1228-x. Epub 2019 May 22. Nature. 2019. PMID: 31118511 Free PMC article.
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Lei Y, VanPortfliet JJ, Chen YF, Bryant JD, Li Y, Fails D, Torres-Odio S, Ragan KB, Deng J, Mohan A, Wang B, Brahms ON, Yates SD, Spencer M, Tong CW, Bosenberg MW, West LC, Shadel GS, Shutt TE, Upton JW, Li P, West AP. Lei Y, et al. Among authors: west lc, west ap. Cell. 2023 Jul 6;186(14):3013-3032.e22. doi: 10.1016/j.cell.2023.05.039. Epub 2023 Jun 22. Cell. 2023. PMID: 37352855 Free PMC article.
195 results