Karpen SJ - Search Results

1

Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury.

Truong JK, Bennett AL, Klindt C, Donepudi AC, Malla SR, Pachura KJ, Zaufel A, Moustafa T, Dawson PA, Karpen SJ. Truong JK, et al. Among authors: karpen sj. J Lipid Res. 2022 Sep;63(9):100261. doi: 10.1016/j.jlr.2022.100261. Epub 2022 Aug 5. J Lipid Res. 2022. PMID: 35934110 Free PMC article.

2

Impaired bile acid handling and aggravated liver injury in mice expressing a hepatocyte-specific RXRα variant lacking the DNA-binding domain.

Kosters A, Felix JC, Desai MS, Karpen SJ. Kosters A, et al. Among authors: karpen sj. J Hepatol. 2014 Feb;60(2):362-9. doi: 10.1016/j.jhep.2013.09.026. Epub 2013 Oct 10. J Hepatol. 2014. PMID: 24120911 Free PMC article.

3

Bile acids reach out to the spinal cord: new insights to the pathogenesis of itch and analgesia in cholestatic liver disease.

Dawson PA, Karpen SJ. Dawson PA, et al. Among authors: karpen sj. Hepatology. 2014 Apr;59(4):1638-41. doi: 10.1002/hep.26786. Epub 2014 Feb 14. Hepatology. 2014. PMID: 24532150 Free PMC article.

4

Not all (bile acids) who wander are lost: the first report of a patient with an isolated NTCP defect.

Karpen SJ, Dawson PA. Karpen SJ, et al. Hepatology. 2015 Jan;61(1):24-7. doi: 10.1002/hep.27294. Epub 2014 Nov 20. Hepatology. 2015. PMID: 24995605 Free PMC article. No abstract available.

5

Intestinal transport and metabolism of bile acids.

Dawson PA, Karpen SJ. Dawson PA, et al. Among authors: karpen sj. J Lipid Res. 2015 Jun;56(6):1085-99. doi: 10.1194/jlr.R054114. Epub 2014 Sep 10. J Lipid Res. 2015. PMID: 25210150 Free PMC article. Review.

6

Inflammation-associated upregulation of the sulfated steroid transporter Slc10a6 in mouse liver and macrophage cell lines.

Kosters A, Abebe DF, Felix JC, Dawson PA, Karpen SJ. Kosters A, et al. Among authors: karpen sj. Hepatol Res. 2016 Jul;46(8):794-803. doi: 10.1111/hepr.12609. Epub 2015 Nov 19. Hepatol Res. 2016. PMID: 26510996 Free PMC article.

7

Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives.

Arab JP, Karpen SJ, Dawson PA, Arrese M, Trauner M. Arab JP, et al. Among authors: karpen sj. Hepatology. 2017 Jan;65(1):350-362. doi: 10.1002/hep.28709. Epub 2016 Aug 4. Hepatology. 2017. PMID: 27358174 Free PMC article. Review.

8

Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice.

Rao A, Kosters A, Mells JE, Zhang W, Setchell KD, Amanso AM, Wynn GM, Xu T, Keller BT, Yin H, Banton S, Jones DP, Wu H, Dawson PA, Karpen SJ. Rao A, et al. Among authors: karpen sj. Sci Transl Med. 2016 Sep 21;8(357):357ra122. doi: 10.1126/scitranslmed.aaf4823. Sci Transl Med. 2016. PMID: 27655848 Free PMC article.

9

Organic solute transporter-β (SLC51B) deficiency in two brothers with congenital diarrhea and features of cholestasis.

Sultan M, Rao A, Elpeleg O, Vaz FM, Abu-Libdeh B, Karpen SJ, Dawson PA. Sultan M, et al. Among authors: karpen sj. Hepatology. 2018 Aug;68(2):590-598. doi: 10.1002/hep.29516. Epub 2018 May 11. Hepatology. 2018. PMID: 28898457 Free PMC article.

10

Attenuation of the Hepatoprotective Effects of Ileal Apical Sodium Dependent Bile Acid Transporter (ASBT) Inhibition in Choline-Deficient L-Amino Acid-Defined (CDAA) Diet-Fed Mice.

Rao A, van de Peppel IP, Gumber S, Karpen SJ, Dawson PA. Rao A, et al. Among authors: karpen sj. Front Med (Lausanne). 2020 Feb 25;7:60. doi: 10.3389/fmed.2020.00060. eCollection 2020. Front Med (Lausanne). 2020. PMID: 32158763 Free PMC article.

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