Cheng X - Search Results

1

HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription.

Huang P, Peslak SA, Ren R, Khandros E, Qin K, Keller CA, Giardine B, Bell HW, Lan X, Sharma M, Horton JR, Abdulmalik O, Chou ST, Shi J, Crossley M, Hardison RC, Cheng X, Blobel GA. Huang P, et al. Among authors: cheng x. Nat Genet. 2022 Sep;54(9):1417-1426. doi: 10.1038/s41588-022-01152-6. Epub 2022 Aug 8. Nat Genet. 2022. PMID: 35941187 Free PMC article.

2

Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase.

Sawada K, Yang Z, Horton JR, Collins RE, Zhang X, Cheng X. Sawada K, et al. Among authors: cheng x. J Biol Chem. 2004 Oct 8;279(41):43296-306. doi: 10.1074/jbc.M405902200. Epub 2004 Jul 29. J Biol Chem. 2004. PMID: 15292170 Free PMC article.

3

Structural basis for inhibition of histamine N-methyltransferase by diverse drugs.

Horton JR, Sawada K, Nishibori M, Cheng X. Horton JR, et al. Among authors: cheng x. J Mol Biol. 2005 Oct 21;353(2):334-344. doi: 10.1016/j.jmb.2005.08.040. J Mol Biol. 2005. PMID: 16168438 Free PMC article.

4

Structure of the SANT domain from the Xenopus chromatin remodeling factor ISWI.

Horton JR, Elgar SJ, Khan SI, Zhang X, Wade PA, Cheng X. Horton JR, et al. Among authors: cheng x. Proteins. 2007 Jun 1;67(4):1198-202. doi: 10.1002/prot.21352. Proteins. 2007. PMID: 17377988 Free PMC article. No abstract available.

5

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.

Lan F, Collins RE, De Cegli R, Alpatov R, Horton JR, Shi X, Gozani O, Cheng X, Shi Y. Lan F, et al. Among authors: cheng x. Nature. 2007 Aug 9;448(7154):718-22. doi: 10.1038/nature06034. Nature. 2007. PMID: 17687328 Free PMC article.

6

The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules.

Collins RE, Northrop JP, Horton JR, Lee DY, Zhang X, Stallcup MR, Cheng X. Collins RE, et al. Among authors: cheng x. Nat Struct Mol Biol. 2008 Mar;15(3):245-50. doi: 10.1038/nsmb.1384. Epub 2008 Feb 10. Nat Struct Mol Biol. 2008. PMID: 18264113 Free PMC article.

7

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix.

Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X. Hashimoto H, et al. Among authors: cheng x. Nature. 2008 Oct 9;455(7214):826-9. doi: 10.1038/nature07280. Epub 2008 Sep 3. Nature. 2008. PMID: 18772888 Free PMC article.

8

UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.

Hashimoto H, Horton JR, Zhang X, Cheng X. Hashimoto H, et al. Among authors: cheng x. Epigenetics. 2009 Jan;4(1):8-14. doi: 10.4161/epi.4.1.7370. Epub 2009 Jan 10. Epigenetics. 2009. PMID: 19077538 Free PMC article.

9

Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.

Chang Y, Zhang X, Horton JR, Upadhyay AK, Spannhoff A, Liu J, Snyder JP, Bedford MT, Cheng X. Chang Y, et al. Among authors: cheng x. Nat Struct Mol Biol. 2009 Mar;16(3):312-7. doi: 10.1038/nsmb.1560. Epub 2009 Feb 15. Nat Struct Mol Biol. 2009. PMID: 19219047 Free PMC article.

10

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.

Horton JR, Upadhyay AK, Qi HH, Zhang X, Shi Y, Cheng X. Horton JR, et al. Among authors: cheng x. Nat Struct Mol Biol. 2010 Jan;17(1):38-43. doi: 10.1038/nsmb.1753. Epub 2009 Dec 20. Nat Struct Mol Biol. 2010. PMID: 20023638 Free PMC article.

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