Medici G - Search Results

1

Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder.

Tassinari M, Mottolese N, Galvani G, Ferrara D, Gennaccaro L, Loi M, Medici G, Candini G, Rimondini R, Ciani E, Trazzi S. Tassinari M, et al. Among authors: medici g. Int J Mol Sci. 2022 Aug 5;23(15):8719. doi: 10.3390/ijms23158719. Int J Mol Sci. 2022. PMID: 35955854 Free PMC article.

2

CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder.

Trazzi S, De Franceschi M, Fuchs C, Bastianini S, Viggiano R, Lupori L, Mazziotti R, Medici G, Lo Martire V, Ren E, Rimondini R, Zoccoli G, Bartesaghi R, Pizzorusso T, Ciani E. Trazzi S, et al. Among authors: medici g. Hum Mol Genet. 2018 May 1;27(9):1572-1592. doi: 10.1093/hmg/ddy064. Hum Mol Genet. 2018. PMID: 29474534

3

Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder.

Fuchs C, Gennaccaro L, Trazzi S, Bastianini S, Bettini S, Lo Martire V, Ren E, Medici G, Zoccoli G, Rimondini R, Ciani E. Fuchs C, et al. Among authors: medici g. Neural Plast. 2018 May 27;2018:9726950. doi: 10.1155/2018/9726950. eCollection 2018. Neural Plast. 2018. PMID: 29977282 Free PMC article.

4

CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling.

Fuchs C, Medici G, Trazzi S, Gennaccaro L, Galvani G, Berteotti C, Ren E, Loi M, Ciani E. Fuchs C, et al. Among authors: medici g. Brain Pathol. 2019 Sep;29(5):658-674. doi: 10.1111/bpa.12716. Epub 2019 Mar 22. Brain Pathol. 2019. PMID: 30793413 Free PMC article.

5

Functional and Structural Impairments in the Perirhinal Cortex of a Mouse Model of CDKL5 Deficiency Disorder Are Rescued by a TrkB Agonist.

Ren E, Roncacé V, Trazzi S, Fuchs C, Medici G, Gennaccaro L, Loi M, Galvani G, Ye K, Rimondini R, Aicardi G, Ciani E. Ren E, et al. Among authors: medici g. Front Cell Neurosci. 2019 Apr 30;13:169. doi: 10.3389/fncel.2019.00169. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31114483 Free PMC article.

6

Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder.

Fuchs C, Gennaccaro L, Ren E, Galvani G, Trazzi S, Medici G, Loi M, Conway E, Devinsky O, Rimondini R, Ciani E. Fuchs C, et al. Among authors: medici g. Neuropharmacology. 2020 May 1;167:107746. doi: 10.1016/j.neuropharm.2019.107746. Epub 2019 Aug 27. Neuropharmacology. 2020. PMID: 31469994

7

Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons.

Loi M, Trazzi S, Fuchs C, Galvani G, Medici G, Gennaccaro L, Tassinari M, Ciani E. Loi M, et al. Among authors: medici g. Mol Neurobiol. 2020 May;57(5):2244-2262. doi: 10.1007/s12035-020-01884-8. Epub 2020 Jan 30. Mol Neurobiol. 2020. PMID: 32002787

8

Correction to: Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons.

Loi M, Trazzi S, Fuchs C, Galvani G, Medici G, Gennaccaro L, Tassinari M, Ciani E. Loi M, et al. Among authors: medici g. Mol Neurobiol. 2020 May;57(5):2263-2264. doi: 10.1007/s12035-020-01890-w. Mol Neurobiol. 2020. PMID: 32064577

9

A GABA_B receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder.

Gennaccaro L, Fuchs C, Loi M, Roncacè V, Trazzi S, Ait-Bali Y, Galvani G, Berardi AC, Medici G, Tassinari M, Ren E, Rimondini R, Giustetto M, Aicardi G, Ciani E. Gennaccaro L, et al. Among authors: medici g. Neurobiol Dis. 2021 Jun;153:105304. doi: 10.1016/j.nbd.2021.105304. Epub 2021 Feb 20. Neurobiol Dis. 2021. PMID: 33621640 Free article.

10

Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder.

Loi M, Gennaccaro L, Fuchs C, Trazzi S, Medici G, Galvani G, Mottolese N, Tassinari M, Giorgini RR, Milelli A, Ciani E. Loi M, et al. Among authors: medici g. Int J Mol Sci. 2021 May 31;22(11):5950. doi: 10.3390/ijms22115950. Int J Mol Sci. 2021. PMID: 34073043 Free PMC article.

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