Newgard CB - Search Results

1

Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice.

Yenilmez B, Kelly M, Zhang GF, Wetoska N, Ilkayeva OR, Min K, Rowland L, DiMarzio C, He W, Raymond N, Lifshitz L, Pan M, Han X, Xie J, Friedline RH, Kim JK, Gao G, Herman MA, Newgard CB, Czech MP. Yenilmez B, et al. Among authors: newgard cb. J Biol Chem. 2022 Oct;298(10):102401. doi: 10.1016/j.jbc.2022.102401. Epub 2022 Aug 18. J Biol Chem. 2022. PMID: 35988648 Free PMC article.

2

Hepatic expression of a targeting subunit of protein phosphatase-1 in streptozotocin-diabetic rats reverses hyperglycemia and hyperphagia despite depressed glucokinase expression.

Yang R, Newgard CB. Yang R, et al. Among authors: newgard cb. J Biol Chem. 2003 Jun 27;278(26):23418-25. doi: 10.1074/jbc.M213112200. Epub 2003 Apr 15. J Biol Chem. 2003. PMID: 12697773 Free article.

3

Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue.

Boucher A, Lu D, Burgess SC, Telemaque-Potts S, Jensen MV, Mulder H, Wang MY, Unger RH, Sherry AD, Newgard CB. Boucher A, et al. Among authors: newgard cb. J Biol Chem. 2004 Jun 25;279(26):27263-71. doi: 10.1074/jbc.M401167200. Epub 2004 Apr 7. J Biol Chem. 2004. PMID: 15073188 Free article.

4

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

Koves TR, Li P, An J, Akimoto T, Slentz D, Ilkayeva O, Dohm GL, Yan Z, Newgard CB, Muoio DM. Koves TR, et al. Among authors: newgard cb. J Biol Chem. 2005 Sep 30;280(39):33588-98. doi: 10.1074/jbc.M507621200. Epub 2005 Aug 3. J Biol Chem. 2005. PMID: 16079133 Free article.

5

Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.

Jensen MV, Joseph JW, Ilkayeva O, Burgess S, Lu D, Ronnebaum SM, Odegaard M, Becker TC, Sherry AD, Newgard CB. Jensen MV, et al. Among authors: newgard cb. J Biol Chem. 2006 Aug 4;281(31):22342-22351. doi: 10.1074/jbc.M604350200. Epub 2006 Jun 1. J Biol Chem. 2006. PMID: 16740637 Free article.

6

A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion.

Ronnebaum SM, Ilkayeva O, Burgess SC, Joseph JW, Lu D, Stevens RD, Becker TC, Sherry AD, Newgard CB, Jensen MV. Ronnebaum SM, et al. Among authors: newgard cb. J Biol Chem. 2006 Oct 13;281(41):30593-602. doi: 10.1074/jbc.M511908200. Epub 2006 Aug 15. J Biol Chem. 2006. PMID: 16912049 Free article.

7

The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion.

Joseph JW, Jensen MV, Ilkayeva O, Palmieri F, Alárcon C, Rhodes CJ, Newgard CB. Joseph JW, et al. Among authors: newgard cb. J Biol Chem. 2006 Nov 24;281(47):35624-32. doi: 10.1074/jbc.M602606200. Epub 2006 Sep 25. J Biol Chem. 2006. PMID: 17001083 Free article.

8

Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes.

Li LO, Mashek DG, An J, Doughman SD, Newgard CB, Coleman RA. Li LO, et al. Among authors: newgard cb. J Biol Chem. 2006 Dec 1;281(48):37246-55. doi: 10.1074/jbc.M604427200. Epub 2006 Oct 6. J Biol Chem. 2006. PMID: 17028193 Free article.

9

Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.

Zhang YM, Chohnan S, Virga KG, Stevens RD, Ilkayeva OR, Wenner BR, Bain JR, Newgard CB, Lee RE, Rock CO, Jackowski S. Zhang YM, et al. Among authors: newgard cb. Chem Biol. 2007 Mar;14(3):291-302. doi: 10.1016/j.chembiol.2007.01.013. Chem Biol. 2007. PMID: 17379144 Free PMC article.

10

Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance.

Nagle CA, An J, Shiota M, Torres TP, Cline GW, Liu ZX, Wang S, Catlin RL, Shulman GI, Newgard CB, Coleman RA. Nagle CA, et al. Among authors: newgard cb. J Biol Chem. 2007 May 18;282(20):14807-15. doi: 10.1074/jbc.M611550200. Epub 2007 Mar 27. J Biol Chem. 2007. PMID: 17389595 Free PMC article.

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