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A hyperactive mutant of interferon-regulatory factor 4.
Kang CH, Hartmann E, Menke L, Staudenraus D, Abass EF, Raifer H, Porapu A, Camara B, Brüstle A, Pinkenburg O, Bieringer M, Lohoff M. Kang CH, et al. Among authors: lohoff m. Eur J Immunol. 2019 May;49(5):812-815. doi: 10.1002/eji.201847530. Epub 2018 Sep 30. Eur J Immunol. 2019. PMID: 30218581 Free article.
Dynamics of humoral and T-cell immunity after three BNT162b2 vaccinations in adults older than 80 years.
Romero-Olmedo AJ, Schulz AR, Hochstätter S, Gupta DD, Hirseland H, Staudenraus D, Camara B, Volland K, Hefter V, Sapre S, Krähling V, Müller-Kräuter H, Chung HR, Mei HE, Keller C, Lohoff M. Romero-Olmedo AJ, et al. Among authors: lohoff m. Lancet Infect Dis. 2022 May;22(5):588-589. doi: 10.1016/S1473-3099(22)00219-5. Epub 2022 Apr 6. Lancet Infect Dis. 2022. PMID: 35397209 Free PMC article. No abstract available.
IRF4 at the crossroads of effector T-cell fate decision.
Huber M, Lohoff M. Huber M, et al. Among authors: lohoff m. Eur J Immunol. 2014 Jul;44(7):1886-95. doi: 10.1002/eji.201344279. Epub 2014 Jun 16. Eur J Immunol. 2014. PMID: 24782159 Free article. Review.
Unlike αβ T cells, γδ T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22.
Raifer H, Mahiny AJ, Bollig N, Petermann F, Hellhund A, Kellner K, Guralnik A, Reinhard K, Bothur E, Huber M, Bauer S, Löhning M, Kiss EA, Ganal SC, Diefenbach A, Korn T, Lohoff M. Raifer H, et al. Among authors: lohoff m. Eur J Immunol. 2012 Dec;42(12):3189-201. doi: 10.1002/eji.201142155. Epub 2012 Oct 17. Eur J Immunol. 2012. PMID: 22961652 Free article.
IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity.
Das Gupta D, Paul C, Samel N, Bieringer M, Staudenraus D, Marini F, Raifer H, Menke L, Hansal L, Camara B, Roth E, Daum P, Wanzel M, Mernberger M, Nist A, Bauer UM, Helmprobst F, Buchholz M, Roth K, Bastian L, Hartmann AM, Baldus C, Ikuta K, Neubauer A, Burchert A, Jäck HM, Klein M, Bopp T, Stiewe T, Pagenstecher A, Lohoff M. Das Gupta D, et al. Among authors: lohoff m. Cell Death Differ. 2022 Nov;29(11):2163-2176. doi: 10.1038/s41418-022-01005-z. Epub 2022 Apr 22. Cell Death Differ. 2022. PMID: 35459909 Free PMC article.
c-Rel promotes type 1 and type 17 immune responses during Leishmania major infection.
Reinhard K, Huber M, Wostl C, Hellhund A, Toboldt A, Abass E, Casper B, Joeris T, Herr C, Bals R, Steinhoff U, Lohoff M, Visekruna A. Reinhard K, et al. Among authors: lohoff m. Eur J Immunol. 2011 May;41(5):1388-98. doi: 10.1002/eji.201041056. Epub 2011 Apr 11. Eur J Immunol. 2011. PMID: 21469108 Free article.
Induction of robust cellular and humoral immunity against SARS-CoV-2 after a third dose of BNT162b2 vaccine in previously unresponsive older adults.
Romero-Olmedo AJ, Schulz AR, Hochstätter S, Das Gupta D, Virta I, Hirseland H, Staudenraus D, Camara B, Münch C, Hefter V, Sapre S, Krähling V, Müller-Kräuter H, Widera M, Mei HE, Keller C, Lohoff M. Romero-Olmedo AJ, et al. Among authors: lohoff m. Nat Microbiol. 2022 Feb;7(2):195-199. doi: 10.1038/s41564-021-01046-z. Epub 2022 Jan 10. Nat Microbiol. 2022. PMID: 35013593
111 results