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NRF2 mediates melanoma addiction to GCDH by modulating apoptotic signalling.
Verma S, Crawford D, Khateb A, Feng Y, Sergienko E, Pathria G, Ma CT, Olson SH, Scott D, Murad R, Ruppin E, Jackson M, Ronai ZA. Verma S, et al. Among authors: jackson m. Nat Cell Biol. 2022 Sep;24(9):1422-1432. doi: 10.1038/s41556-022-00985-x. Epub 2022 Sep 1. Nat Cell Biol. 2022. PMID: 36050469 Free PMC article.
Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11.
Feng Y, Lau E, Scortegagna M, Ruller C, De SK, Barile E, Krajewski S, Aza-Blanc P, Williams R, Pinkerton AB, Jackson M, Chin L, Pellecchia M, Bosenberg M, Ronai ZA. Feng Y, et al. Among authors: jackson m. Pigment Cell Melanoma Res. 2013 Jan;26(1):136-42. doi: 10.1111/pcmr.12033. Epub 2012 Nov 2. Pigment Cell Melanoma Res. 2013. PMID: 23035722 Free PMC article.
Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells.
Feng Y, Sessions EH, Zhang F, Ban F, Placencio-Hickok V, Ma CT, Zeng FY, Pass I, Terry DB, Cadwell G, Bankston LA, Liddington RC, Chung TDY, Pinkerton AB, Sergienko E, Gleave M, Bhowmick NA, Jackson MR, Cherkasov A, Ronai ZA. Feng Y, et al. Among authors: jackson mr. Cancer Lett. 2019 May 1;449:145-162. doi: 10.1016/j.canlet.2019.02.012. Epub 2019 Feb 14. Cancer Lett. 2019. PMID: 30771432 Free PMC article.
Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators.
Pinkerton AB, Sessions EH, Hershberger P, Maloney PR, Peddibhotla S, Hopf M, Sergienko E, Ma CT, Smith LH, Jackson MR, Tanaka J, Tsuji T, Akiu M, Cohen SE, Nakamura T, Gardell SJ. Pinkerton AB, et al. Among authors: jackson mr. Bioorg Med Chem Lett. 2021 Jun 1;41:128007. doi: 10.1016/j.bmcl.2021.128007. Epub 2021 Mar 31. Bioorg Med Chem Lett. 2021. PMID: 33798699
The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors.
Khateb A, Deshpande A, Feng Y, Finlay D, Lee JS, Lazar I, Fabre B, Li Y, Fujita Y, Zhang T, Yin J, Pass I, Livneh I, Jeremias I, Burian C, Mason JR, Almog R, Horesh N, Ofran Y, Brown K, Vuori K, Jackson M, Ruppin E, Deshpande AJ, Ronai ZA. Khateb A, et al. Among authors: jackson m. Nat Commun. 2021 Sep 13;12(1):5397. doi: 10.1038/s41467-021-25664-7. Nat Commun. 2021. PMID: 34518534 Free PMC article.
Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex.
Feng Y, Grotegut S, Jovanovic P, Gandin V, Olson SH, Murad R, Beall A, Colayco S, De-Jesus P, Chanda S, English BP, Singer RH, Jackson M, Topisirovic I, Ronai ZA. Feng Y, et al. Among authors: jackson m. Front Pharmacol. 2022 Dec 1;13:1029093. doi: 10.3389/fphar.2022.1029093. eCollection 2022. Front Pharmacol. 2022. PMID: 36532738 Free PMC article.
5,119 results