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Novel therapeutic approaches to post-infarction remodelling.
Fraccarollo D, Galuppo P, Bauersachs J. Fraccarollo D, et al. Among authors: galuppo p. Cardiovasc Res. 2012 May 1;94(2):293-303. doi: 10.1093/cvr/cvs109. Epub 2012 Mar 2. Cardiovasc Res. 2012. PMID: 22387461 Review.
The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling.
Galuppo P, Vettorazzi S, Hövelmann J, Scholz CJ, Tuckermann JP, Bauersachs J, Fraccarollo D. Galuppo P, et al. FASEB J. 2017 Nov;31(11):5122-5132. doi: 10.1096/fj.201700317R. Epub 2017 Aug 2. FASEB J. 2017. PMID: 28768721 Free PMC article.
In summary, GR signaling in macrophages, playing a crucial role in tissue-repairing mechanisms, could be a potential therapeutic target during wound healing after ischemic myocardial injury.-Galuppo, P., Vettorazzi, S., Hovelmann, J., Scholz, C.-J., Tuckermann, J. …
In summary, GR signaling in macrophages, playing a crucial role in tissue-repairing mechanisms, could be a potential therapeutic target duri …
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