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Farnesoid X receptor antagonizes macrophage-dependent licensing of effector T lymphocytes and progression of sclerosing cholangitis.
Shi T, Malik A, Yang Vom Hofe A, Matuschek L, Mullen M, Lages CS, Kudira R, Singh R, Zhang W, Setchell KDR, Hildeman D, Pasare C, Wagner B, Miethke AG. Shi T, et al. Among authors: setchell kdr. Sci Transl Med. 2022 Dec 14;14(675):eabi4354. doi: 10.1126/scitranslmed.abi4354. Epub 2022 Dec 14. Sci Transl Med. 2022. PMID: 36516265 Free PMC article.
Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency.
Setchell KD, Heubi JE, Shah S, Lavine JE, Suskind D, Al-Edreesi M, Potter C, Russell DW, O'Connell NC, Wolfe B, Jha P, Zhang W, Bove KE, Knisely AS, Hofmann AF, Rosenthal P, Bull LN. Setchell KD, et al. Gastroenterology. 2013 May;144(5):945-955.e6; quiz e14-5. doi: 10.1053/j.gastro.2013.02.004. Epub 2013 Feb 13. Gastroenterology. 2013. PMID: 23415802 Free PMC article.
Treatment of bile acid amidation defects with glycocholic acid.
Heubi JE, Setchell KD, Jha P, Buckley D, Zhang W, Rosenthal P, Potter C, Horslen S, Suskind D. Heubi JE, et al. Hepatology. 2015 Jan;61(1):268-74. doi: 10.1002/hep.27401. Epub 2014 Dec 23. Hepatology. 2015. PMID: 25163551 Free PMC article.
255 results