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Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages.
Okombo J, Mok S, Qahash T, Yeo T, Bath J, Orchard LM, Owens E, Koo I, Albert I, Llinás M, Fidock DA. Okombo J, et al. Among authors: koo i. PLoS Pathog. 2022 Oct 28;18(10):e1010926. doi: 10.1371/journal.ppat.1010926. eCollection 2022 Oct. PLoS Pathog. 2022. PMID: 36306287 Free PMC article.
The underappreciated diversity of bile acid modifications.
Mohanty I, Mannochio-Russo H, Schweer JV, El Abiead Y, Bittremieux W, Xing S, Schmid R, Zuffa S, Vasquez F, Muti VB, Zemlin J, Tovar-Herrera OE, Moraïs S, Desai D, Amin S, Koo I, Turck CW, Mizrahi I, Kris-Etherton PM, Petersen KS, Fleming JA, Huan T, Patterson AD, Siegel D, Hagey LR, Wang M, Aron AT, Dorrestein PC. Mohanty I, et al. Among authors: koo i. Cell. 2024 Mar 28;187(7):1801-1818.e20. doi: 10.1016/j.cell.2024.02.019. Epub 2024 Mar 11. Cell. 2024. PMID: 38471500 Free article.
Effects of Early Life Exposures to the Aryl Hydrocarbon Receptor Ligand TCDF on Gut Microbiota and Host Metabolic Homeostasis in C57BL/6J Mice.
Tian Y, Rimal B, Bisanz JE, Gui W, Wolfe TM, Koo I, Murray IA, Nettleford SK, Yokoyama S, Dong F, Koshkin S, Prabhu KS, Turnbaugh PJ, Walk ST, Perdew GH, Patterson AD. Tian Y, et al. Among authors: koo i. Environ Health Perspect. 2024 Aug;132(8):87005. doi: 10.1289/EHP13356. Epub 2024 Aug 14. Environ Health Perspect. 2024. PMID: 39140734 Free PMC article.
Complex chemical signals dictate Ah receptor activation through the gut-lung axis.
Dong F, Murray IA, Annalora A, Coslo D, Desai D, Gowda K, Yang J, Wang D, Koo I, Hao F, Amin SG, Patterson AD, Marcus C, Perdew GH. Dong F, et al. Among authors: koo i. bioRxiv [Preprint]. 2023 Apr 5:2023.02.22.529529. doi: 10.1101/2023.02.22.529529. bioRxiv. 2023. Update in: FASEB J. 2023 Jul;37(7):e23010. doi: 10.1096/fj.202300703R. PMID: 36865156 Free PMC article. Updated. Preprint.
107 results