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Biomarkers of tumor-reactive CD4+ and CD8+ TILs associate with improved prognosis in endometrial cancer.
Palomero J, Panisello C, Lozano-Rabella M, Tirtakasuma R, Díaz-Gómez J, Grases D, Pasamar H, Arregui L, Dorca Duch E, Guerra Fernández E, Vivancos A, de Andrea CE, Melero I, Ponce J, Vidal A, Piulats JM, Matias-Guiu X, Gros A. Palomero J, et al. Among authors: melero i. J Immunother Cancer. 2022 Dec;10(12):e005443. doi: 10.1136/jitc-2022-005443. J Immunother Cancer. 2022. PMID: 36581331 Free PMC article.
Immunodivergence in Metastatic Colorectal Cancer.
de Andrea CE, Schalper KA, Sanmamed MF, Melero I. de Andrea CE, et al. Among authors: melero i. Cancer Cell. 2018 Dec 10;34(6):876-878. doi: 10.1016/j.ccell.2018.11.012. Cancer Cell. 2018. PMID: 30537510 Free PMC article.
Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.
Perez-Ruiz E, Minute L, Otano I, Alvarez M, Ochoa MC, Belsue V, de Andrea C, Rodriguez-Ruiz ME, Perez-Gracia JL, Marquez-Rodas I, Llacer C, Alvarez M, de Luque V, Molina C, Teijeira A, Berraondo P, Melero I. Perez-Ruiz E, et al. Among authors: melero i. Nature. 2019 May;569(7756):428-432. doi: 10.1038/s41586-019-1162-y. Epub 2019 May 1. Nature. 2019. PMID: 31043740 Free article.
Immunotherapeutic effects of intratumoral nanoplexed poly I:C.
Aznar MA, Planelles L, Perez-Olivares M, Molina C, Garasa S, Etxeberría I, Perez G, Rodriguez I, Bolaños E, Lopez-Casas P, Rodriguez-Ruiz ME, Perez-Gracia JL, Marquez-Rodas I, Teijeira A, Quintero M, Melero I. Aznar MA, et al. Among authors: melero i. J Immunother Cancer. 2019 May 2;7(1):116. doi: 10.1186/s40425-019-0568-2. J Immunother Cancer. 2019. PMID: 31046839 Free PMC article.
Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells.
Etxeberria I, Bolaños E, Quetglas JI, Gros A, Villanueva A, Palomero J, Sánchez-Paulete AR, Piulats JM, Matias-Guiu X, Olivera I, Ochoa MC, Labiano S, Garasa S, Rodriguez I, Vidal A, Mancheño U, Hervás-Stubbs S, Azpilikueta A, Otano I, Aznar MA, Sanmamed MF, Inogés S, Berraondo P, Teijeira Á, Melero I. Etxeberria I, et al. Among authors: melero i. Cancer Cell. 2019 Dec 9;36(6):613-629.e7. doi: 10.1016/j.ccell.2019.10.006. Epub 2019 Nov 21. Cancer Cell. 2019. PMID: 31761658 Free article.
Cellular cytotoxicity is a form of immunogenic cell death.
Minute L, Teijeira A, Sanchez-Paulete AR, Ochoa MC, Alvarez M, Otano I, Etxeberrria I, Bolaños E, Azpilikueta A, Garasa S, Casares N, Perez Gracia JL, Rodriguez-Ruiz ME, Berraondo P, Melero I. Minute L, et al. Among authors: melero i. J Immunother Cancer. 2020 Mar;8(1):e000325. doi: 10.1136/jitc-2019-000325. J Immunother Cancer. 2020. PMID: 32217765 Free PMC article.
CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity.
Teijeira Á, Garasa S, Gato M, Alfaro C, Migueliz I, Cirella A, de Andrea C, Ochoa MC, Otano I, Etxeberria I, Andueza MP, Nieto CP, Resano L, Azpilikueta A, Allegretti M, de Pizzol M, Ponz-Sarvisé M, Rouzaut A, Sanmamed MF, Schalper K, Carleton M, Mellado M, Rodriguez-Ruiz ME, Berraondo P, Perez-Gracia JL, Melero I. Teijeira Á, et al. Among authors: melero i. Immunity. 2020 May 19;52(5):856-871.e8. doi: 10.1016/j.immuni.2020.03.001. Epub 2020 Apr 13. Immunity. 2020. PMID: 32289253 Free article.
Human CD8 T cells are susceptible to TNF-mediated activation-induced cell death.
Otano I, Alvarez M, Minute L, Ochoa MC, Migueliz I, Molina C, Azpilikueta A, de Andrea CE, Etxeberria I, Sanmamed MF, Teijeira Á, Berraondo P, Melero I. Otano I, et al. Among authors: melero i. Theranostics. 2020 Mar 15;10(10):4481-4489. doi: 10.7150/thno.41646. eCollection 2020. Theranostics. 2020. PMID: 32292509 Free PMC article.
372 results