Wang N - Search Results

1

Exploration of novel hexahydropyrrolo[1,2-e]imidazol-1-one derivatives as antiviral agents against ZIKV and USUV.

Chen R, Francese R, Wang N, Li F, Sun X, Xu B, Liu J, Liu Z, Donalisio M, Lembo D, Zhou GC. Chen R, et al. Among authors: wang n. Eur J Med Chem. 2023 Feb 15;248:115081. doi: 10.1016/j.ejmech.2022.115081. Epub 2023 Jan 3. Eur J Med Chem. 2023. PMID: 36623328

2

Rapid generation of novel benzoic acid-based xanthine derivatives as highly potent, selective and long acting DPP-4 inhibitors: Scaffold-hopping and prodrug study.

Li Q, Meng L, Zhou S, Deng X, Wang N, Ji Y, Peng Y, Xing J, Yao G. Li Q, et al. Among authors: wang n. Eur J Med Chem. 2019 Oct 15;180:509-523. doi: 10.1016/j.ejmech.2019.07.045. Epub 2019 Jul 16. Eur J Med Chem. 2019. PMID: 31336309

3

Discovery of ZFD-10 of a pyridazino[4,5-b]indol-4(5H)-one derivative as an anti-ZIKV agent and a ZIKV NS5 RdRp inhibitor.

Zhou GF, Qian W, Li F, Yang RH, Wang N, Zheng CB, Li CY, Gu XR, Yang LM, Liu J, Xiong SD, Zhou GC, Zheng YT. Zhou GF, et al. Among authors: wang n. Antiviral Res. 2023 Jun;214:105607. doi: 10.1016/j.antiviral.2023.105607. Epub 2023 Apr 21. Antiviral Res. 2023. PMID: 37088168

4

Discovery of 2,4,6-trisubstituted pyrimidine derivatives as novel potent HIV-1 NNRTIs by exploiting the tolerant region II of the NNIBP.

Zhou Z, Sun Y, Qin Y, Wang N, Zhao F, Wang Z, Clercq E, Pannecouque C, Zhan P, Kang D, Liu X. Zhou Z, et al. Among authors: wang z, wang n. Eur J Med Chem. 2024 Nov 5;277:116708. doi: 10.1016/j.ejmech.2024.116708. Epub 2024 Jul 27. Eur J Med Chem. 2024. PMID: 39094273

5

Design, synthesis, and evaluation of chalcone derivatives as xanthine oxidase inhibitors.

Xu H, Yang C, Li L, Du J, Yin Q, Zhao P, Wang N, Huang W, Li Y. Xu H, et al. Among authors: wang n. Eur J Med Chem. 2024 Dec 5;279:116893. doi: 10.1016/j.ejmech.2024.116893. Epub 2024 Sep 25. Eur J Med Chem. 2024. PMID: 39348762

6

Identification of novel uracil derivatives incorporating benzoic acid moieties as highly potent Dipeptidyl Peptidase-IV inhibitors.

Huang J, Deng X, Zhou S, Wang N, Qin Y, Meng L, Li G, Xiong Y, Fan Y, Guo L, Lan D, Xing J, Jiang W, Li Q. Huang J, et al. Among authors: wang n. Bioorg Med Chem. 2019 Feb 15;27(4):644-654. doi: 10.1016/j.bmc.2019.01.001. Epub 2019 Jan 4. Bioorg Med Chem. 2019. PMID: 30642693

7

The protective effects of natural product tunicatachalcone against neuroinflammation via targeting RIPK2 in microglia BV-2 cells stimulated by LPS.

Wen R, Lv J, Jia P, Yang W, Wang N, Wu X, Xue Z, Liu Y. Wen R, et al. Among authors: wang n. Bioorg Med Chem. 2022 Sep 1;69:116916. doi: 10.1016/j.bmc.2022.116916. Epub 2022 Jul 2. Bioorg Med Chem. 2022. PMID: 35792403

8

Structure-Based Design of Novel G-Protein-Coupled Receptor TAAR1 Agonists as Potential Antipsychotic Drug Candidates.

Zhou Z, Zhang W, Zhao F, Sun Y, Wang N, Cheng J, Zhan P, Yang F, Sun JP, Liu X, Kang D. Zhou Z, et al. Among authors: wang n. J Med Chem. 2024 Mar 14;67(5):4234-4249. doi: 10.1021/acs.jmedchem.4c00195. Epub 2024 Feb 28. J Med Chem. 2024. PMID: 38416116

9

Discovery of Novel Aryl Triazolone Dihydropyridines (ATDPs) Targeting Highly Conserved Residue W229 as Promising HIV-1 NNRTIs.

Sun Y, Zhou Z, Wang N, Zhao F, Liu Y, Xu X, Wang X, Gou Z, De Clercq E, Pannecouque C, Zhan P, Kang D, Liu X. Sun Y, et al. Among authors: wang x, wang n. J Med Chem. 2024 Apr 25;67(8):6570-6584. doi: 10.1021/acs.jmedchem.4c00026. Epub 2024 Apr 13. J Med Chem. 2024. PMID: 38613773

10

Development of amphipathic derivatives of thymol and carvacrol as potent broad-spectrum antibacterial agents.

Dong H, You Y, Wang N, Wang M, Song T, He Y, Zou Y, He Y, Peng T, Mei L. Dong H, et al. Among authors: wang n, wang m. Eur J Med Chem. 2024 Oct 5;276:116716. doi: 10.1016/j.ejmech.2024.116716. Epub 2024 Jul 26. Eur J Med Chem. 2024. PMID: 39088997

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