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NHC-gold compounds mediate immune suppression through induction of AHR-TGFβ1 signalling in vitro and in scurfy mice.
Cheng X, Haeberle S, Shytaj IL, Gama-Brambila RA, Theobald J, Ghafoory S, Wölker J, Basu U, Schmidt C, Timm A, Taškova K, Bauer AS, Hoheisel J, Tsopoulidis N, Fackler OT, Savarino A, Andrade-Navarro MA, Ott I, Lusic M, Hadaschik EN, Wölfl S. Cheng X, et al. Among authors: basu u. Commun Biol. 2020 Jan 3;3:10. doi: 10.1038/s42003-019-0716-8. eCollection 2020. Commun Biol. 2020. PMID: 31909202 Free PMC article.
In-vitro and in-vivo investigations into the carbene-gold anticancer drug candidates NHC*-Au-SCSNMe2 and NHC*-Au-S-GLUC against advanced prostate cancer PC3.
Walther W, Althagafi D, Curran D, O'Beirne C, Mc Carthy C, Ott I, Basu U, Büttner B, Sterner-Kock A, Müller-Bunz H, Sánchez-Sanz G, Zhu X, Tacke M. Walther W, et al. Among authors: basu u. Anticancer Drugs. 2020 Aug;31(7):672-683. doi: 10.1097/CAD.0000000000000930. Anticancer Drugs. 2020. PMID: 32282370
[(C C)Au(N N)]+ Complexes as a New Family of Anticancer Candidates: Synthesis, Characterization and Exploration of the Antiproliferative Properties.
Khodjoyan S, Remadna E, Dossmann H, Lesage D, Gontard G, Forté J, Hoffmeister H, Basu U, Ott I, Spence P, Waller ZAE, Salmain M, Bertrand B. Khodjoyan S, et al. Among authors: basu u. Chemistry. 2021 Nov 11;27(63):15773-15785. doi: 10.1002/chem.202102751. Epub 2021 Oct 5. Chemistry. 2021. PMID: 34436799
Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain-like Protease PLpro.
Gil-Moles M, Türck S, Basu U, Pettenuzzo A, Bhattacharya S, Rajan A, Ma X, Büssing R, Wölker J, Burmeister H, Hoffmeister H, Schneeberg P, Prause A, Lippmann P, Kusi-Nimarko J, Hassell-Hart S, McGown A, Guest D, Lin Y, Notaro A, Vinck R, Karges J, Cariou K, Peng K, Qin X, Wang X, Skiba J, Szczupak Ł, Kowalski K, Schatzschneider U, Hemmert C, Gornitzka H, Milaeva ER, Nazarov AA, Gasser G, Spencer J, Ronconi L, Kortz U, Cinatl J, Bojkova D, Ott I. Gil-Moles M, et al. Among authors: basu u. Chemistry. 2021 Dec 20;27(71):17928-17940. doi: 10.1002/chem.202103258. Epub 2021 Nov 23. Chemistry. 2021. PMID: 34714566 Free PMC article.
265 results