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A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, Han J, Ryu S, Tare A, Zhu Y, Hudgins A, Atzmon G, Barzilai N, Wolfe A, Moody K, Garcia BA, Robbins PD, Vijg J, Seluanov A, Suh Y, Gorbunova V. Simon M, et al. Among authors: han j. EMBO J. 2023 Feb 1;42(3):e113326. doi: 10.15252/embj.2022113326. EMBO J. 2023. PMID: 36722290 Free PMC article.
Genetic signature of human longevity in PKC and NF-κB signaling.
Ryu S, Han J, Norden-Krichmar TM, Zhang Q, Lee S, Zhang Z, Atzmon G, Niedernhofer LJ, Robbins PD, Barzilai N, Schork NJ, Suh Y. Ryu S, et al. Among authors: han j. Aging Cell. 2021 Jul;20(7):e13362. doi: 10.1111/acel.13362. Epub 2021 Jul 1. Aging Cell. 2021. PMID: 34197020 Free PMC article.
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, Han J, Ryu S, Tare A, Zhu Y, Hudgins A, Atzmon G, Barzilai N, Wolfe A, Moody K, Garcia BA, Thomas DD, Robbins PD, Vijg J, Seluanov A, Suh Y, Gorbunova V. Simon M, et al. Among authors: han j. EMBO J. 2022 Nov 2;41(21):e110393. doi: 10.15252/embj.2021110393. Epub 2022 Oct 10. EMBO J. 2022. PMID: 36215696 Free PMC article.
Recruitment of CTCF to the SIRT1 promoter after Oxidative Stress mediates Cardioprotective Transcription.
Wagner T, Priyanka P, Micheletti R, Friedman MJ, Nair SJ, Gamliel A, Taylor H, Song X, Cho M, Oh S, Li W, Han J, Ohgi KA, Abrass M, D'Antonio-Chronowska A, D'Antonio M, Hazuda H, Duggirala R, Blangero J, Ding S, Guzmann C, Frazer KA, Aggarwal AK, Zemljic-Harpf AE, Rosenfeld MG, Suh Y. Wagner T, et al. Among authors: han j. bioRxiv [Preprint]. 2024 May 22:2024.05.17.594600. doi: 10.1101/2024.05.17.594600. bioRxiv. 2024. PMID: 38798402 Free PMC article. Preprint.
A GSDMD agonist boosts specific antitumor immunity.
Zhang Y, Han J. Zhang Y, et al. Among authors: han j. Cell Res. 2024 Nov 13. doi: 10.1038/s41422-024-01051-x. Online ahead of print. Cell Res. 2024. PMID: 39538026 No abstract available.
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