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Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma.
Frias A, Di Leo L, Antoranz A, Nazerai L, Carretta M, Bodemeyer V, Pagliuca C, Dahl C, Claps G, Mandelli GE, Andhari MD, Pacheco MP, Sauter T, Robert C, Guldberg P, Madsen DH, Cecconi F, Bosisio FM, De Zio D. Frias A, et al. Among authors: guldberg p. J Immunother Cancer. 2023 Mar;11(3):e006389. doi: 10.1136/jitc-2022-006389. J Immunother Cancer. 2023. PMID: 36868570 Free PMC article.
DNA methyltransferase inhibition promotes recruitment of myeloid-derived suppressor cells to the tumor microenvironment through induction of tumor cell-intrinsic interleukin-1.
Traynor S, Terp MG, Nielsen AY, Guldberg P, Jakobsen M, Pedersen PG, Gammelgaard OL, Pedersen CB, Pedersen MT, Rattenborg S, Ditzel HJ, Gjerstorff MF. Traynor S, et al. Among authors: guldberg p. Cancer Lett. 2023 Jan 1;552:215982. doi: 10.1016/j.canlet.2022.215982. Epub 2022 Oct 27. Cancer Lett. 2023. PMID: 36309209 Free article.
AMBRA1 levels predict resistance to MAPK inhibitors in melanoma.
Di Leo L, Pagliuca C, Kishk A, Rizza S, Tsiavou C, Pecorari C, Dahl C, Pacheco MP, Tholstrup R, Brewer JR, Berico P, Hernando E, Cecconi F, Ballotti R, Bertolotto C, Filomeni G, Gjerstorff MF, Sauter T, Lovat P, Guldberg P, De Zio D. Di Leo L, et al. Among authors: guldberg p. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2400566121. doi: 10.1073/pnas.2400566121. Epub 2024 Jun 13. Proc Natl Acad Sci U S A. 2024. PMID: 38870061
NAD+ regulates nucleotide metabolism and genomic DNA replication.
Munk SHN, Merchut-Maya JM, Adelantado Rubio A, Hall A, Pappas G, Milletti G, Lee M, Johnsen LG, Guldberg P, Bartek J, Maya-Mendoza A. Munk SHN, et al. Among authors: guldberg p. Nat Cell Biol. 2023 Dec;25(12):1774-1786. doi: 10.1038/s41556-023-01280-z. Epub 2023 Nov 13. Nat Cell Biol. 2023. PMID: 37957325 Free PMC article.
Hyper-recombination in ribosomal DNA is driven by long-range resection-independent RAD51 accumulation.
Gál Z, Boukoura S, Oxe KC, Badawi S, Nieto B, Korsholm LM, Geisler SB, Dulina E, Rasmussen AV, Dahl C, Lv W, Xu H, Pan X, Arampatzis S, Stratou DE, Galanos P, Lin L, Guldberg P, Bartek J, Luo Y, Larsen DH. Gál Z, et al. Among authors: guldberg p. Nat Commun. 2024 Sep 6;15(1):7797. doi: 10.1038/s41467-024-52189-6. Nat Commun. 2024. PMID: 39242676 Free PMC article.
Age-related differences in cancer biology in older patients.
Gammelgaard OL, Guldberg P, Gjerstorff MF, Ditzel HJ. Gammelgaard OL, et al. Among authors: guldberg p. Ugeskr Laeger. 2024 Jan 22;186(4):V06230375. doi: 10.61409/V06230375. Ugeskr Laeger. 2024. PMID: 38305317 Free article. Review. Danish.
Adoptive cell transfer therapy with ex vivo primed peripheral lymphocytes in combination with anti-PDL1 therapy effectively inhibits triple-negative breast cancer growth and metastasis.
Gammelgaard OL, Terp MG, Kirkin AF, Johansen S, Traynor S, Vever H, Guldberg P, Kodahl AR, Gjerstorff MF, Ditzel HJ. Gammelgaard OL, et al. Among authors: guldberg p. Mol Cancer. 2024 Jan 6;23(1):6. doi: 10.1186/s12943-023-01914-8. Mol Cancer. 2024. PMID: 38184565 Free PMC article.
211 results