Smith HL - Search Results

1

ASO targeting RBM3 temperature-controlled poison exon splicing prevents neurodegeneration in vivo.

Preußner M, Smith HL, Hughes D, Zhang M, Emmerichs AK, Scalzitti S, Peretti D, Swinden D, Neumann A, Haltenhof T, Mallucci GR, Heyd F. Preußner M, et al. Among authors: smith hl. EMBO Mol Med. 2023 May 8;15(5):e17157. doi: 10.15252/emmm.202217157. Epub 2023 Mar 22. EMBO Mol Med. 2023. PMID: 36946385 Free PMC article.

2

The unfolded protein response: mechanisms and therapy of neurodegeneration.

Smith HL, Mallucci GR. Smith HL, et al. Brain. 2016 Aug;139(Pt 8):2113-21. doi: 10.1093/brain/aww101. Epub 2016 May 11. Brain. 2016. PMID: 27190028 Free PMC article. Review.

3

Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration.

Smith HL, Freeman OJ, Butcher AJ, Holmqvist S, Humoud I, Schätzl T, Hughes DT, Verity NC, Swinden DP, Hayes J, de Weerd L, Rowitch DH, Franklin RJM, Mallucci GR. Smith HL, et al. Neuron. 2020 Mar 4;105(5):855-866.e5. doi: 10.1016/j.neuron.2019.12.014. Epub 2020 Jan 7. Neuron. 2020. PMID: 31924446 Free PMC article.

4

Targeting the kinase insert loop of PERK selectively modulates PERK signaling without systemic toxicity in mice.

Hughes DT, Halliday M, Smith HL, Verity NC, Molloy C, Radford H, Butcher AJ, Mallucci GR. Hughes DT, et al. Among authors: smith hl. Sci Signal. 2020 Aug 11;13(644):eabb4749. doi: 10.1126/scisignal.abb4749. Sci Signal. 2020. PMID: 32788341

5

TrkB signaling regulates the cold-shock protein RBM3-mediated neuroprotection.

Peretti D, Smith HL, Verity N, Humoud I, de Weerd L, Swinden DP, Hayes J, Mallucci GR. Peretti D, et al. Among authors: smith hl. Life Sci Alliance. 2021 Feb 9;4(4):e202000884. doi: 10.26508/lsa.202000884. Print 2021 Apr. Life Sci Alliance. 2021. PMID: 33563652 Free PMC article.

6

Targeting the Unfolded Protein Response as a Disease-Modifying Pathway in Dementia.

Sidhom E, O'Brien JT, Butcher AJ, Smith HL, Mallucci GR, Underwood BR. Sidhom E, et al. Among authors: smith hl. Int J Mol Sci. 2022 Feb 11;23(4):2021. doi: 10.3390/ijms23042021. Int J Mol Sci. 2022. PMID: 35216136 Free PMC article. Review.

7

Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration.

Albert-Gasco H, Smith HL, Alvarez-Castelao B, Swinden D, Halliday M, Janaki-Raman S, Butcher AJ, Mallucci GR. Albert-Gasco H, et al. Among authors: smith hl. Brain. 2024 Feb 1;147(2):649-664. doi: 10.1093/brain/awad313. Brain. 2024. PMID: 37703312 Free PMC article.

8

PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress.

Brar KK, Hughes DT, Morris JL, Subramanian K, Krishna S, Gao F, Rieder LS, Uhrig S, Freeman J, Smith HL, Jukes-Jones R, Avezov E, Nunnari J, Prudent J, Butcher AJ, Mallucci GR. Brar KK, et al. Among authors: smith hl. Science. 2024 Aug 30;385(6712):eadp7114. doi: 10.1126/science.adp7114. Epub 2024 Aug 30. Science. 2024. PMID: 39116259

9

Clinical Characteristics and Care Trajectories of Transgender and Gender Diverse Patients With Cancer Seen in a Pediatric Gender Clinic.

Bono MH, Smith HL, Williams CR, McGregor K, Berman AK, Boskey ER. Bono MH, et al. Among authors: smith hl. Psychooncology. 2024 Nov;33(11):e70017. doi: 10.1002/pon.70017. Psychooncology. 2024. PMID: 39505728

10

Treatment of equine keratomycosis, part 1: selection of appropriate therapy based on clinical presentation and diagnostic testing improves clinical outcomes.

Smith HL, Love KR, Antezana A, Barr EM, Gilger BC, Oh A. Smith HL, et al. J Am Vet Med Assoc. 2024 Oct 23:1-11. doi: 10.2460/javma.24.06.0431. Online ahead of print. J Am Vet Med Assoc. 2024. PMID: 39442544

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