Lu W - Search Results

1

Discovery of novel, potent, and orally bioavailable HDACs inhibitors with LSD1 inhibitory activity for the treatment of solid tumors.

Duan Y, Yu T, Jin L, Zhang S, Shi X, Zhang Y, Zhou N, Xu Y, Lu W, Zhou H, Zhu H, Bai S, Hu K, Guan Y. Duan Y, et al. Among authors: lu w. Eur J Med Chem. 2023 Jun 5;254:115367. doi: 10.1016/j.ejmech.2023.115367. Epub 2023 Apr 14. Eur J Med Chem. 2023. PMID: 37086699

2

Discovery of potent and novel smoothened antagonists via structure-based virtual screening and biological assays.

Lu W, Zhang D, Ma H, Tian S, Zheng J, Wang Q, Luo L, Zhang X. Lu W, et al. Eur J Med Chem. 2018 Jul 15;155:34-48. doi: 10.1016/j.ejmech.2018.05.035. Epub 2018 May 23. Eur J Med Chem. 2018. PMID: 29857275

3

Design, synthesis, and structure--activity-relationship of tetrahydrothiazolopyridine derivatives as potent smoothened antagonists.

Ma H, Lu W, Sun Z, Luo L, Geng D, Yang Z, Li E, Zheng J, Wang M, Zhang H, Yang S, Zhang X. Ma H, et al. Among authors: lu w. Eur J Med Chem. 2015 Jan 7;89:721-32. doi: 10.1016/j.ejmech.2014.11.006. Epub 2014 Nov 4. Eur J Med Chem. 2015. PMID: 25462278

4

Design, synthesis, and structure-activity-relationship of a novel series of CXCR4 antagonists.

Li Z, Wang Y, Fu C, Wang X, Wang JJ, Zhang Y, Zhou D, Zhao Y, Luo L, Ma H, Lu W, Zheng J, Zhang X. Li Z, et al. Among authors: lu w. Eur J Med Chem. 2018 Apr 10;149:30-44. doi: 10.1016/j.ejmech.2018.02.042. Epub 2018 Feb 16. Eur J Med Chem. 2018. PMID: 29494843

5

Structural optimization on a virtual screening hit of smoothened receptor.

Song S, Jiang J, Zhao L, Wang Q, Lu W, Zheng C, Zhang J, Ma H, Tian S, Zheng J, Luo L, Li Y, Yang ZJ, Zhang X. Song S, et al. Among authors: lu w. Eur J Med Chem. 2019 Jun 15;172:1-15. doi: 10.1016/j.ejmech.2019.03.057. Epub 2019 Mar 26. Eur J Med Chem. 2019. PMID: 30939349

6

Scaffold hopping approach to a new series of smoothened antagonists.

Lu W, Geng D, Sun Z, Yang Z, Ma H, Zheng J, Zhang X. Lu W, et al. Bioorg Med Chem Lett. 2014 May 15;24(10):2300-4. doi: 10.1016/j.bmcl.2014.03.079. Epub 2014 Apr 3. Bioorg Med Chem Lett. 2014. PMID: 24726807

7

Chromosome-level genome assembly of the smallscale yellowfin (Plagiognathops microlepis).

Liang Y, Liu H, Lu W, Li J, Fang T, Gao N, Chen C, Zhao X, Yang K, Liu H. Liang Y, et al. Among authors: lu w. Sci Data. 2024 Nov 15;11(1):1234. doi: 10.1038/s41597-024-04105-2. Sci Data. 2024. PMID: 39548126

8

LOXL1 promotes gastric cancer progression by β-catenin-cyclinD mediated proliferation.

Liang JE, Bao BW, He XH, Lu WQ, Liu Y, Wang J, Qu XJ, Li DY, Che XF. Liang JE, et al. Among authors: lu wq. Exp Cell Res. 2024 Nov 13:114331. doi: 10.1016/j.yexcr.2024.114331. Online ahead of print. Exp Cell Res. 2024. PMID: 39547354

9

The gut core microbial species Bifidobacterium longum: Colonization, mechanisms, and health benefits.

Xiao Y, Huang L, Zhao J, Chen W, Lu W. Xiao Y, et al. Among authors: lu w. Microbiol Res. 2024 Nov 7;290:127966. doi: 10.1016/j.micres.2024.127966. Online ahead of print. Microbiol Res. 2024. PMID: 39547052 Review.

10

Treating metabolic dysfunction-associated steatohepatitis: The fat-trimming FGF21 approach.

Li X, Rao Z, Hu W, Lu W, Luo Y. Li X, et al. Among authors: lu w. Obes Rev. 2024 Nov 15:e13861. doi: 10.1111/obr.13861. Online ahead of print. Obes Rev. 2024. PMID: 39546893 Review.

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