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Total Chemical Synthesis of Palmitoyl-Conjugated Insulin.
Liu M, Li Q, Delaine C, Wu H, Arsenakis Y, White BF, Forbes BE, Chandrashekar C, Hossain MA. Liu M, et al. Among authors: delaine c. ACS Omega. 2023 Apr 6;8(15):13715-13720. doi: 10.1021/acsomega.2c07918. eCollection 2023 Apr 18. ACS Omega. 2023. PMID: 37091377 Free PMC article.
Engineering of a Biologically Active Insulin Dimer.
Liu M, White BF, Praveen P, Li W, Lin F, Wu H, Li R, Delaine C, Forbes BE, Wade JD, Hossain MA. Liu M, et al. Among authors: delaine c. J Med Chem. 2021 Dec 9;64(23):17448-17454. doi: 10.1021/acs.jmedchem.1c01594. Epub 2021 Nov 19. J Med Chem. 2021. PMID: 34797669
A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
Xiong X, Menting JG, Disotuar MM, Smith NA, Delaine CA, Ghabash G, Agrawal R, Wang X, He X, Fisher SJ, MacRaild CA, Norton RS, Gajewiak J, Forbes BE, Smith BJ, Safavi-Hemami H, Olivera B, Lawrence MC, Chou DH. Xiong X, et al. Among authors: delaine ca. Nat Struct Mol Biol. 2020 Jul;27(7):615-624. doi: 10.1038/s41594-020-0430-8. Epub 2020 Jun 1. Nat Struct Mol Biol. 2020. PMID: 32483339 Free PMC article.
How ligand binds to the type 1 insulin-like growth factor receptor.
Xu Y, Kong GK, Menting JG, Margetts MB, Delaine CA, Jenkin LM, Kiselyov VV, De Meyts P, Forbes BE, Lawrence MC. Xu Y, et al. Among authors: delaine ca. Nat Commun. 2018 Feb 26;9(1):821. doi: 10.1038/s41467-018-03219-7. Nat Commun. 2018. PMID: 29483580 Free PMC article.
20 results