Chen Y - Search Results

1

YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.

Wang L, Dou X, Chen S, Yu X, Huang X, Zhang L, Chen Y, Wang J, Yang K, Bugno J, Pitroda S, Ding X, Piffko A, Si W, Chen C, Jiang H, Zhou B, Chmura SJ, Luo C, Liang HL, He C, Weichselbaum RR. Wang L, et al. Among authors: chen s, chen c, chen y. Cancer Cell. 2023 Jul 10;41(7):1294-1308.e8. doi: 10.1016/j.ccell.2023.04.019. Epub 2023 May 25. Cancer Cell. 2023. PMID: 37236197 Free PMC article.

2

Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays.

Chen S, Li L, Chen Y, Hu J, Liu J, Liu YC, Liu R, Zhang Y, Meng F, Zhu K, Lu J, Zheng M, Chen K, Zhang J, Jiang H, Yao Z, Luo C. Chen S, et al. Among authors: chen k, chen y. J Chem Inf Model. 2016 Mar 28;56(3):527-34. doi: 10.1021/acs.jcim.5b00738. Epub 2016 Mar 4. J Chem Inf Model. 2016. PMID: 26914852

3

Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay.

Song Y, Li L, Chen Y, Liu J, Xiao S, Lian F, Zhang N, Ding H, Zhang Y, Chen K, Jiang H, Zhang C, Liu YC, Chen S, Luo C. Song Y, et al. Among authors: chen k, chen s, chen y. Bioorg Med Chem. 2018 May 1;26(8):1751-1758. doi: 10.1016/j.bmc.2018.02.020. Epub 2018 Feb 24. Bioorg Med Chem. 2018. PMID: 29534934

4

Design, synthesis and biological evaluation of benzo[cd]indol-2(1H)-ones derivatives as BRD4 inhibitors.

Feng Y, Xiao S, Chen Y, Jiang H, Liu N, Luo C, Chen S, Chen H. Feng Y, et al. Among authors: chen s, chen h, chen y. Eur J Med Chem. 2018 May 25;152:264-273. doi: 10.1016/j.ejmech.2018.04.048. Epub 2018 Apr 28. Eur J Med Chem. 2018. PMID: 29730189

5

Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors.

Zhang L, Chen Y, Liu N, Li L, Xiao S, Li X, Chen K, Luo C, Chen S, Chen H. Zhang L, et al. Among authors: chen k, chen s, chen h, chen y. Bioorg Chem. 2018 Oct;80:649-654. doi: 10.1016/j.bioorg.2018.07.022. Epub 2018 Jul 21. Bioorg Chem. 2018. PMID: 30059890

6

Discovery of a novel 53BP1 inhibitor through AlphaScreen-based high-throughput screening.

Sun Y, Lu H, Fang X, Xiao S, Yang F, Chen Y, Wang H, Li X, Lu J, Lin H, Luo C, Zhao K, Chen S. Sun Y, et al. Among authors: chen s, chen y. Bioorg Med Chem. 2021 Mar 15;34:116054. doi: 10.1016/j.bmc.2021.116054. Epub 2021 Feb 2. Bioorg Med Chem. 2021. PMID: 33571875

7

High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases.

Xiao S, Guo S, Han J, Sun Y, Wang M, Chen Y, Fang X, Yang F, Mu Y, Zhang L, Ding Y, Zhang N, Jiang H, Chen K, Zhao K, Luo C, Chen S. Xiao S, et al. Among authors: chen k, chen s, chen y. Nucleic Acids Res. 2022 Jan 25;50(2):e9. doi: 10.1093/nar/gkab989. Nucleic Acids Res. 2022. PMID: 34718755 Free PMC article.

8

Selective PPARγ modulator diosmin improves insulin sensitivity and promotes browning of white fat.

Yu J, Hu Y, Sheng M, Gao M, Guo W, Zhang Z, Wang D, Wu X, Li J, Chen Y, Zhao W, Liu C, Cui X, Chen X, Zhao C, Chen H, Xiao J, Chen S, Luo C, Xu L, Gu X, Ma X. Yu J, et al. Among authors: chen s, chen x, chen h, chen y. J Biol Chem. 2023 Apr;299(4):103059. doi: 10.1016/j.jbc.2023.103059. Epub 2023 Feb 24. J Biol Chem. 2023. PMID: 36841479 Free PMC article.

9

Inhibition of YTHDF1 by salvianolic acid overcomes gluten-induced intestinal inflammation.

Olazagoitia-Garmendia A, Rojas-Márquez H, Romero MDM, Ruiz P, Agirre-Lizaso A, Chen Y, Perugorria MJ, Herrero L, Serra D, Luo C, Bujanda L, He C, Castellanos-Rubio A. Olazagoitia-Garmendia A, et al. Among authors: chen y. Gut. 2024 Aug 8;73(9):1590-1592. doi: 10.1136/gutjnl-2023-330459. Gut. 2024. PMID: 37907258 Free PMC article. No abstract available.

10

FMRP phosphorylation modulates neuronal translation through YTHDF1.

Zou Z, Wei J, Chen Y, Kang Y, Shi H, Yang F, Shi Z, Chen S, Zhou Y, Sepich-Poore C, Zhuang X, Zhou X, Jiang H, Wen Z, Jin P, Luo C, He C. Zou Z, et al. Among authors: chen s, chen y. Mol Cell. 2023 Dec 7;83(23):4304-4317.e8. doi: 10.1016/j.molcel.2023.10.028. Epub 2023 Nov 9. Mol Cell. 2023. PMID: 37949069 Free article.

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