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7-UP: Generating in silico CODEX from a small set of immunofluorescence markers.
Wu E, Trevino AE, Wu Z, Swanson K, Kim HJ, D'Angio HB, Preska R, Chiou AE, Charville GW, Dalerba P, Duvvuri U, Colevas AD, Levi J, Bedi N, Chang S, Sunwoo J, Egloff AM, Uppaluri R, Mayer AT, Zou J. Wu E, et al. Among authors: chang s. PNAS Nexus. 2023 May 19;2(6):pgad171. doi: 10.1093/pnasnexus/pgad171. eCollection 2023 Jun. PNAS Nexus. 2023. PMID: 37275261 Free PMC article.
Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment.
Moreno-Nieves UY, Tay JK, Saumyaa S, Horowitz NB, Shin JH, Mohammad IA, Luca B, Mundy DC, Gulati GS, Bedi N, Chang S, Chen C, Kaplan MJ, Rosenthal EL, Holsinger FC, Divi V, Baik FM, Sirjani DB, Gentles AJ, Newman AM, Freud AG, Sunwoo JB. Moreno-Nieves UY, et al. Among authors: chang s. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2101169118. doi: 10.1073/pnas.2101169118. Proc Natl Acad Sci U S A. 2021. PMID: 34244432 Free PMC article.
Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA.
Zhang W, Li I, Reticker-Flynn NE, Good Z, Chang S, Samusik N, Saumyaa S, Li Y, Zhou X, Liang R, Kong CS, Le QT, Gentles AJ, Sunwoo JB, Nolan GP, Engleman EG, Plevritis SK. Zhang W, et al. Among authors: chang s. Nat Methods. 2022 Jun;19(6):759-769. doi: 10.1038/s41592-022-01498-z. Epub 2022 Jun 2. Nat Methods. 2022. PMID: 35654951 Free PMC article.
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis.
Reticker-Flynn NE, Zhang W, Belk JA, Basto PA, Escalante NK, Pilarowski GOW, Bejnood A, Martins MM, Kenkel JA, Linde IL, Bagchi S, Yuan R, Chang S, Spitzer MH, Carmi Y, Cheng J, Tolentino LL, Choi O, Wu N, Kong CS, Gentles AJ, Sunwoo JB, Satpathy AT, Plevritis SK, Engleman EG. Reticker-Flynn NE, et al. Among authors: chang s. Cell. 2022 May 26;185(11):1924-1942.e23. doi: 10.1016/j.cell.2022.04.019. Epub 2022 May 6. Cell. 2022. PMID: 35525247 Free PMC article.
PKCα inhibitors promote breast cancer immune evasion by maintaining PD-L1 stability.
Yu J, Xiang Y, Gao Y, Chang S, Kong R, Lv X, Yu J, Jin Y, Li C, Ma Y, Wang Z, Zhou J, Yuan H, Shang S, Hua F, Zhang X, Cui B, Li P. Yu J, et al. Among authors: chang s. Acta Pharm Sin B. 2024 Oct;14(10):4378-4395. doi: 10.1016/j.apsb.2024.08.003. Epub 2024 Aug 8. Acta Pharm Sin B. 2024. PMID: 39525583 Free PMC article.
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